L8: FeLV And FIV (Levy) Flashcards

1
Q

How is FeLV spread

A
  • close contact and body fluids
  • kittens of infected queens
  • housemates
  • fights
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2
Q

How is FIV spread?

A
  • primarily by fighting
  • sexual spread, mother to kittens uncommon
  • most common in adult males
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3
Q

How long does FIV infection last?

A

Lifelong

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4
Q

CS or sequelae of FIV

A
  • very long asymptomatic period

- stomatitis, uveitis, chronic infections, neoplasia (lymphoma, SCC)

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5
Q

Prevalence of FeLV and FIV

A

About 3% of all cats

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6
Q

Cornerstone of reducing exposure to FeLV/FIV

A

Testing!
-test all new pets, all exposed cats 60 days post-exposure, all sick cats, and before vaccination

Vaccination

  • all kittens and at risk adults for FeLV
  • at risk for FIV

Segregate infected from uninfected

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7
Q

Test FeLV for Ag or Ab?

A

Ag

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8
Q

Test FIV for Ag or Ab?

A

Ab

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9
Q

Confirmatory testing for FeLV***

A

1) IFA: has poor sensitivity, so only helpful if positive***
2) PCR

Should repeat testing monthly to detect regressive infection, esp. In kittens

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10
Q

Confirmatory testing for FIV**

A

1) PCR (only useful if positive)
2) Western blot (doesn’t add info)
3) Witness test can tell difference between vaccinated cat and FIV positive cat

-kittens born to FIV+ queens will have colostral Ab up to 5 months of age but are usually not infected (segregate and retest monthly)

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11
Q

See diagnostic algorithms in pics

A

:)

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12
Q

Mixing FIV positive and negative cats unlikely to be a problem unless the cats fight, but can try to segregate with a screen

A

:)

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13
Q

FeLV vaccination

A
  • AAFP says only vax at risk cats and most kittens
  • Dr. Levy says vaccinate all cats for FeLV, boost at 1 year, then evaluate life-style risk
  • test before vaccinating
  • not all cats protected by vaccine
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14
Q

FIV vaccination

A
  • not recommended for routine use
  • interferes w/ FIV diagnosis
  • may use for “at risk”
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15
Q

Prevention in clinics of FIV/FeLV

A
  • avoid iatrogenic transmission
  • screen blood donors
  • clean instruments
  • spay and neuter before 5 months
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16
Q

Management of FeLV and FIV infected cats

A
  • many healthy infected cats remain healthy for years
  • many sick infected respond well to specific tx
  • little evidence to support use of immunomodulators or antivirals
  • avoid stress, vaccinate as usual
17
Q

Survival of cats after FeLV dx

A
  • half alive at 3 years

- one third alive at 6 years (from time of dx)

18
Q

Survival of cats after FIV diagnosis

A
  • 94% at 3 years

- 80% at 6 years

19
Q

Best practices in shelters

A
  • test all cats before adoption
  • advise adopters to retest in 60 days
  • don’t expose FeLV and FIV infected cats to uninfected cats
  • vaccinate against FeLV
  • retest cats in long-term care
  • testing of individually housed cats NOT essential
  • testing cats prior to group housing IS essential
20
Q

Outcomes of FeLV

A
  • progressive (ineffective immune system)
  • regressive
  • abortive

*mostly lifelong