L7 Ocular Pharmacology/Cataracts Flashcards
Components of Ocular Surface Immunity
- Defence Mechanisms
- Things that compromise defenses
_____________________:
- Excellent Gram +ve cover:
- bacterial conjunctivitis
- prevention of infection (post corneal abrasion)
- Does NOT cover gram -ve (Pseudomonas)
- No oral/IV form. VERY Little developed resistance
Chloramphenicol
- Excellent Gram +ve cover:
- bacterial conjunctivitis
- prevention of infection (post corneal abrasion)
- Does NOT cover gram -ve (Pseudomonas) - Ofloxacin
- No oral/IV form. VERY Little developed resistance
_____________________:
- Used for infection after cataracts surgery
- Gram +ve cover
- Increasing resistance
Fusidic Acid:
- Used for infection after cataracts surgery
- Gram +ve cover
- Increasing resistance
____________________: Pseudomonal cover (contact lens-related infection)
Ofloxacin: Pseudomonal cover (contact lens related infection)
What broad-spectrum antibiotics are used to treat ophthalmic conditions? When are these needed?
_____________________:
- Dendritic ulcers due to HSV
- PO Aciclovir used for HS uveitis
Aciclovir Ointment:
- Dendritic ulcers due to HSV
- PO Aciclovir used for HS uveitis
_____________________:
- Acanthamoeba keratitis
- Ocular surface toxicity
Brolene + Chlorhexidene
- Acanthamoeba keratitis (Keratitis/dendritic ulcers. DO NOT use steroids for this => geographic ulcers)
- Ocular surface toxicity
When are Topical Steroids called for?
Side Effects?
Paths of innervation for Miosis/Mydriasis?
Mydriatic Agents and their Indications?
Miotic Agents and their Indications?
What is Aniscoria and what can cause it?
RAPD vs. Aniscoria
Aniscoria: Difference in pupil size caused by damage to EFFERENT limb or IRIS. Caused by:
- CN III Palsy
- Horner’s Pupil (Loss Of Parasympathetic)
- Adies Pupil (Loss of Sympathetic)
RAPD (Relative Afferent Pupillary Deffect): Casued by damage to AFFERENT Limb (CN II or Retina)
Manifestation/Cause/Investigation of Adie’s Pupil?
Triad/Cause/Investigation of Horner’s Syndrome?
Occular Antihypertensive with risk of increase eyelash length and Pigmentation of the iris?
MOA?
Prostaglandin (PG) Analogues (Bimatoprost)
MOA: INCR Aqueous Outflow
Occular Antihypertensive with risk of bronchospasm/bradycardia that should be avoided in asthma?
MOA?
Beta Blocker (Betaxolol)
MOA: DEC Aqueous Production
Occular Antihypertensive with risk of Karatitis?
MOA?
Alpha agonists (Epinephrine)
MOA: DEC Aqueous Production
Drug with potential side effect of Maculopathy?
Hydroxychloroquine
Drug with the potential side effect of Corneal Deposits (Vortex Keratopathy)?
Amiodarone
Drug with potential side effect of Glaucoma/Cataracts?
Steroids
Drug with potential side effect of Pigmentary Retinopathy?
Tamoxifen
Symptoms/Signs of Cataracts?
Cataracts (Loss of transparency of the natural lens)
Causes/Misconceptions about Cataracts?
Cataracts (Loss of transparency of the natural lens)
Treatment of Cataracts?
