L7 Connective Tissue Flashcards
What are the functions of CT?
-structural support & attachment for the tissues & organs of the body
-metabolic functions
-blood components & blood vessels
-defensive functions
Formation of CT starts with cells of CT will lay down the ______ substance as a ____ containing various kinds of macromolecules
ground
gel
Formation ( 2nd Step )
______ cells will then secrete macromolecules ( fibrous protein ) into the ______ substance.
Fibroblasts
ground
Formation ( 3rd step )
The _________ will assemble & form large insoluble _____________.
protein fibers
fibrous aggregates
Formation ( 4th Step )
CT _____ & provide tissues with ___________.
matures
mechanical strength
What are the cell components of CT?
Fibroblasts
Macrophages
Plasma
Mast
Adipocytes
Fibroblasts are _____, ____ cells with ______ processes.
large
flat
branching
Macrophages have an _______ shape with _____ branching projections and are capable of engulfing ____________ and __________ by _________.
irregular
short
bacteria
cellular debris
phagocytosis
Plasma cells develop from _______ lymphocyte. They secrete _______ and are found in __________ and _______ tracts.
B
antibodies
GI
respiratory
Mast cells are abundant alongside the _________ the supply the CT. They produce __________ and can also _____ bacteria.
blood vessels
histamine
kill
Adipocytes are CT cells that store _________ and found in the _____ and ______.
triglycerides ( fats )
heart
kidneys
Extracellular matrix is made up of _______ and ___________.
protein fibers
ground substance
Ground substance occupies space between the ____ and _____ of CT. It contains ____and large________.
cells
fibers
water
organic molecules
What are the 3 types of fibers?
Collagen
Elastic
Reticular
Collagen fibers resists _______ tension and adds great ______ strength to the tissue.
pulling
tensile
Collagen fibers consists of the ______ collagen and are found in _______, ______,______ and ______.
protein
bone
cartilage
tendons
ligaments
Elastic fibers branch and join together to form a _________ network within a tissue.
fibrous
An elastic fiber consists of ____ which adds ___ and______. They are found in ___________,___________,___________.
fibrillin
strength
stability
skin
blood vessel walls
lung tissue
Reticular fibers are produced by ______ and provide ______ and _______. They form ______ of many organs such as _____ and ______.
Fibroblasts
support
strength
stroma ( covering )
spleen
lymph nodes
CT is divided into ___________,_________ and__________
Dense
Loose
Specialized
Dense regular CT consists of ______ fibers arranged in bundles with ____ in between the bundles.
collagen
fibroblasts
Locations of dense regular CT are?
tendons
ligaments
Dense irregular CT contains ______ packed, woven meshes of _____ fibers that are _____ arranged.
tightly
collagen
irregular
Locations of dense irregular CT?
-fibrous pericardium of heart
-periosteum of bone
-perichondrium of cartilage
What is Marfan Syndrome?
An inherited disorder caused by a defective fibrillin syndrome which results in abnormal development of elastic fibers.
Tissues rich in elastic fibers are malformed or weakened.
Most life-threatening - weakening of aorta
What is sjogren’s syndrome?
A chronic autoimmune inflammatory disease which moisture producing glands are damaged. Decreasing quantity and quantity of saliva and tears.
