L7 - Acid Base Balance pt 1- Intro to buffers. Flashcards
1
Q
Why is pH regulated?
A
Proteins in our body are pH sensitive.
2
Q
What type of sclae is pH measured on?
A
Logarithmic, -log10[H+]
3
Q
At what pH do most body fluids sit?
A
6.8-8.0
4
Q
What plasma pH is classed as acidosis?
A
-7.35
5
Q
What plasma pH is classed as alkalosis?
A
+7.45
6
Q
What systems are involved in the regulation of pH?
A
- Blood and tissue buffers
- Respiration (excrete or retain Co2)
- Renal (allows for direct secretion of alkali)
7
Q
What is the primary extracelluar fluid buffer?
A
Carbonic Acid/ Bicarbonate
8
Q
What is the Henderson-Hasselbach equation?
A
Used to determine the pH of a buffer
- pH= pk+log [HCO3]/[H2CO3]
- where pk is a constant at 37 degrees - (6.1)
