L7

Question 1

What is the coenzyme form of folic acid and what enzyme is responsible for the conversion ?

Answer 1

tetrahydrofolate . folic acid is absorbed and converted to tetrahydrofolate by folate reductase

Question 2

what is the function of folic acid ?

Answer 2

it is required for DNA synthesis , and thus , cell division . also prevents neural tube defects

Question 3

tetrahydrofolar and what other compound activate eachother ?

Answer 3

cobalamin (B12)

Question 4

For b12 to be absorbed in the GIT we require ___

Answer 4

intrinsic factor of castle (secreted by parital cells of stomach)

Question 5

what releases B12 from dietary proteins in the stomach ?

Answer 5

HCL

Question 6

Although vitamin B12 is water soluble , it can be stored in ____ as____

Answer 6

the liver , as cobalamin

Question 7

cobalin converts methylmalonyl CoA TO WHAT ?

Answer 7

succinyl CoA

Question 8

what is the source of vitamin b12?

Answer 8

synthesized only by microorganisms , so it is only in animal products

Question 9

what would pernicious anemia (Autoimmune antibody generated against intrinsic factor) result in ?

Answer 9

vitamin B12 deficiency