L6 Epitheia Flashcards
what are the main functions of epithelial tissues?
protection filtration sensation absorption secretion
what are the 3 types of structures the link cells to another and the basal lamina?
tight junctions
anchoring junctions
channel forming junctions
describe tight junctions and there purpose
seal adjacent cells- prevents leaking between cells from bacteria and viruses. also prevent migration of membrane proetins- create cell polarity
how are anchoring junctions categorised and what are the 2 main types?
they are categories by cytoskeletal filaments they interact with.
actin filament attachments or intermediate filament attachments
describe actin filament attachments
Cell-cell= adherent junction
cell-basal lamina- focal adhesions
describe intermediate filaments
cell-cell- desmosomes
cell-basal lamina- hemidesmosomes
what is the basal lamina?
underlines all epithelia
strong flexible foundation a meshwork of different proteins
what are the 4 proteins which the basal lamina is made up from?
lamina
type IV collagen
entactin
Perlacan
what is the basement membrane
combination of the basal lamina and the reticular lamina (mainly composed of type III collagen)
what are the 3 main function of the basement membrane
anchoring of epithelial cells to connect tissue .
mechanical barrier
important in angiogenesis
describe gap junctions and there function?
form tiny intracellular channels
allow diffusion between cells. cell cell communication by movement of ions etc
describe simple squamous epithelial tissue function/position
flat, one layer
absorption, filtration, minimal barrier for diffusion. found in capillaries alveoli and pleural cavities
describe simple cuboidal function and position?
secretion/transportation
found in glands, ducts, and kidney tubules also cover ovaries
describe the simple columnar tissue function and position?
function- absorption, protection,secretion
postion- digestive tract, may have microvilli to increase SA
describer stratified squamous function and position
lost of layers of flat cells
provide protection can be keratinised in the top layer, will die if become too keratinised and then are shed!
found in the skin, mouth, upper throat and oesophagus