L5 Resting Membrane Potential

Question 1

What is the resting membrane potential of our nerve and muscle cells?

Answer 1

-70 mV

Question 2

Which ion contributes the most to our resting membrane potential?

Answer 2

K+ because it has a higher permeability than N+

More K+ leak channels than Na+ leak channels

Question 3

What is the equilibrium potential for K+ in our cells?

Answer 3

-90 mV

Question 4

What is the equilibrium potential for Na+ in our cells?

Answer 4

+65 mV

Question 5

What does Ohm’s Law/Goldman’s equation calculate?

Answer 5

Resting membrane potential

Question 6

What is the Goldman/Ohm’s equation/

Answer 6

Em= (gk Ek + gNa ENa) / (gK + gNa)

G=permeability

Question 7

A hypernatremic state would depolarize or hyperpolarize the membrane?

Answer 7

Depolarize (make it more positive)

Question 8

A hyperkalemic state would depolarize or hyperpolarize the membrane?

Answer 8

Depolarize (make it more positive)

Question 9

Would hypokalemia hyperpolarize or depolarize the membrane?

Answer 9

Hyperpolarize

Hypokalemic patients are paralyzed

Question 10

Would hyponatremia depolarize or hyperpolarize the membrane?

Answer 10

Hyperpolarize

Make it more negative