L4 Equilibrium Potentials Flashcards
What is the ratio of K+ inside:outside
150mM inside
5mM outside
What is the ratio of Na+ outside:inside the cell?
15 mM inside
150mM outside
What is the ratio of Cl- outside:inside the cell?
120mM outside
10mM inside
At rest, there are leaky K+ and Na+ channels. What are they doing?
K+ is leaking out of the cell a LOT
Na+ is leaking into the cell a little
When will the net flux of an ion stop?
When the electrical gradient and chemical gradient of it are equal
What does the Nernst equation calculate?
Calculates the equilibrium potential for an ion at a given concentration difference across the membrane (AS LONG AS THE MEMBRANE IS PERMEABLE TO THAT ION)
-determines the electrical forces required to just balance a given diffusion force ([ion in]-[ion out]
What is the Nernst Equation?
E ion=
(60/z) log([ion out]/[ion in])
What percentage of ions move across the membrane during changes in membrane potential
Infinitesimally small