L5 - Cytoskeleton And Extracellular Matrix Flashcards

1
Q

Components of cytoskeleton

A

Microtubules, microfilament, intermediate filaments

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2
Q

Mirctobulues

A

Made of tubular dimmers

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3
Q

Mircofilaments

A

Made of actin subunits, twisted in rope like structure

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4
Q

Intermediate filaments

A

Made of keratin proteins or a fibrous subunit. Tightly twisted together

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5
Q

Microtubules resist…

A

Compression

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6
Q

Microtubules come from…

A

The centrosome, allows for organisation of Microtubules

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7
Q

Microtubules make…

A

Flagella or cilia

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8
Q

Flagella

A

Snake like motion

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9
Q

Cilia

A

Rowing like motion

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10
Q

Microtubules are involved in…

A

Organelle motility, ATP powered motor proteins walk along microtubules

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11
Q

The ‘cell highway’

A

Microtubules

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12
Q

Microfilaments are…

A

Linear strands, 3D networks using branching proteins

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13
Q

Microfilaments resist…

A

Tension

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14
Q

Microfilaments are in…

A

The cortical network, under the plasma membrane to give cell structure.

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15
Q

Microfilaments work in…

A

Actin-myosin interactions to allow muscle cell contractions

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16
Q

Non animal examples of microfilaments

A

Ameboid movement, cytoplasmic streaming

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17
Q

Intermediate filaments are…

A

Made from various proteins depending on the cell function

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18
Q

Intermediate filaments are…

A

Supercoiled into cables, more long lasting and less dynamic

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19
Q

Intermediate filaments are for…

A

More permanent structure

20
Q

Intermediate filaments help…

A

Maintain cell shape, anchor organelles

21
Q

Intermediate filaments remain

A

After cell death the filaments remain and allow for protection in skin

22
Q

Tight junctions

A

Hold neighbouring cells pressed tightly together prevents movement of fluid across cells

23
Q

Desmosomes

A

Anchoring junction, act as rivets

24
Q

Desmosomes made of

A

Very strong preoriens

25
Desmosomes are connected to
Intermediate filaments
26
Tight junctions connected too
Microfilaments
27
Gap junctions
Contact between cytoplasm of two cells
28
Gap junction purpose
Allow rapid cell to cell communication and small molecules pass from cell to cell
29
Gap junction strength
Weak
30
Tight junctions
Prayer hand
31
Desmosomes
Linked hands
32
Gap junctions
Tube hands
33
Extra Cellular Matrix are…
Dependant on the tissues, made by cells
34
ECM
Extra Cellular Matrix
35
ECM example
Bone tissue, cartilage, connective tissue
36
ECM
Is made of secreted materials from constitutive exocytosis
37
ECM proteins
Glycoproteins, proteins with added carbohydrates
38
Abundant glycoprotein
Collagen
39
Glycoproteins
Protein with added carbohydrates
40
Collagen fibers are held in
Proteoglycan complex matrix
41
Proteoglycans
Proteins with added sugar
42
Proteoglycan purpose
Trap water within the ECM
43
Fibroneftins
Attach cells to ECM
44
integrins
Connect ECM to cytoskeleton
45
Connection purpose
Provide a communication link from ECM to the cells interior