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SP17 Perio II > L5 > Flashcards

L5 Flashcards

1
Q

When is it reasonable to consider antibiotics to treat chronic perio?

A

Test positive for Pg or AA

When no response to initial therapy and more AL

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2
Q

Two most common antibiotics

A

8 days of
Penicillins (amoxicillin (500mg)
Metronidazole (250mg)

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3
Q

Narrow spectrum antibiotic example

A

metronidazol

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4
Q

Broad spectrum antibiotic example

A

Tetracycline

Azithromycin

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5
Q

Augmentin

A

amoxicillin combined with beta lactamase inhibitor

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6
Q

Amoxicillin
Spectrum
Against

A

Broad spectrum

Good against negative

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7
Q

Metronidazole
Spectrum
Against

A 
Narrow spectrum
Strict anaerobes (NOT good against AA)
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8
Q

Tetracycline
Static/cidal
Spectrum
Mechanism

A

Static
Broad spectrum
Inhibits collagenase

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9
Q

Tetracycline accumulates in

A

epithelial cells
gingival fibroblasts
PMNs

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10
Q

Fluoroquinolones
Static/cidal
Spectrum

A

Cidal

Extremely active against AA, less against Pg

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11
Q

Clindamycin
Static/cidal
Spectrum

A

Static

Strict anaerobes, less against facultative (AA)

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12
Q

Macrolides

A

Azithromycin

Clarithromycin

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13
Q

Macrolides

Spectrum

A

AA, Pg, ,negative bacteria

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14
Q

Macrolides taken up by

A

Epithelial cells
PMNs
Fibroblasts

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15
Q

affects of Azithromycin

A

Decrease IL-8 and TNF in GCF

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16
Q

Azithromycin regimen

A

500mg starting dose

250mg for 4 days

17
Q

Metronidazole reigmen

A

500mg for 7 days

SP17 Perio II (9 decks)

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