L4 Flashcards
When are systemic antibiotics indicated
Aggressive
Secondary systemic involvemnt
Some types of chronic
Bisphosphonates
Use
Side effects
Incapacitates osteoclasts, reducing bone resorption
Osteomalacia
Modest effect on bone density, no effect on AL
NSAIDS
Use
Effects
Inhibit biosynthesis of prostaglandins
Reduces gingival inflammation, effects on attachment levels are modest
Periostat
Dose
Length
Low dose (20mg) doxycyclin hyclate 4 months
Periostat
location
Inhibits
concentrates in GCF, uses cementum as reservoir
Inhibits MMP-8 (tissue destructive enzymes)
Periochip
Collagen gel as a carrier for chlorhexidine
Atridox
Co-polymer carrier w/ doxycycline
Arestin
Microspheres w/ minocyclin
Indication for local antimicrobial delivery
Slight to moderate chronic w/ greater or equal to 5mm b/c will fall out if shallower