L5 Flashcards
1
Q
What causes sickle cell anemia?
A
HbS replacing HbF
2
Q
What does sickle anemia lead to?
A
Blockage of blood causing localized anoxia
3
Q
Name a characteristic of sickle cell anemia RBCs
A
They adhere/stick to vessel walls
4
Q
What are the symptoms of sickle cell anemia?
A
Stroke, splenic and renal dysfunction
5
Q
How to diagnose Sickle cell anemia?
A
Via electrophoresis of hemoglobin in which HbS moves towards the anode
6
Q
How to treat sickle cell anemia?
A
Via hydration, RBC transfusions, stem cell transplantation