L4: Sensation and Perception (+ brain devices) Flashcards
what are ways we can study the brain in humans? list 4
EEG
PET
MRI + fMRI
Lesion studies
what are two possible faults for each technique of studying the brain
spatial resolution:
- how clearly we can distinguish between brain regions
- Low SR = lines blur not as clear
- High SR = can see exactly where everything is
Temporal resolution:
- resolve differences in the brain activity over time
- high TR = you can find the brain activity changing per millisecond
- low TR = cant see signaling in brain as fast
1 Brain technique: Electroencephalography (EEG)
what, why, how, record on graph?, sleep/brain wave connection
- what: measures the electrical activity in the brain -the activation of synapses (not firing rate)
- why: useful in arousal, consciousness + epilepsy studies
- how: measures the neurons via electrodes that are placed above
- record: potential difference (volts) over time (seconds)
- sleep:
awake: low amp, high freq
sleep: high amp, low freq
REM: low amp, hig freq - breaks the rules
use it to diagnose sleep disorders
EEG: how good is the temporal res and spatial res?
Great temporal resolution (biggest advantage)
* Millisecond scale
* Great for measuring rapid changes in arousal/consciousness (regular EEG) and rapid cognitive processes (ERP)
Poor spatial resolution (biggest disadvantage)
* Difficult to determine which specific areas are active
* Deeper brain areas cannot be measured
useful for studying fast signaling, bad at locating regions
2 Brain technique: Positron Emission Tomography (PET)
what, why, how, example with glucose
what: measures activity in the brain using a synthetic radiotracer that is injected in the subject
how: This radiotracer reacts with tissue in the brain; this reaction produces a signal that can be measured with specialized equipment
why:
Two general purposes:
* Measuring metabolic activity
* Characterizing distribution of specific substances
glucose:
* If the radiotracer is similar to glucose (such as Fluorodeoxyglucose (18F)), it will be distributed in the same way (i.e. to active neurons)
* Signal differences between brain regions reflect differences in glucose demands (+ neuronal activity)
PET: how good is the temporal res and spatial res?
implication in psychology?
Decent spatial resolution
* Better than EEG but worse than MRI
Poor temporal resolution
* Difficult to resolve rapid changes in neural activity
- Due to its resolution issues, PET is no longer preferred as a structural/functional measure in psychology
- It does have other very important uses in neuroscience and medicine (but you won’t need to know these)
3 Brain Techniques: MRI/fMRI
what, MRI and disorders/MDD, how (fMRI), fMRI for behavior and disorders, con for fMRI
what:
MRI is for assessing structure–one of the best. fMRI, can be used for assessing function.
MRI and MDD:
Major depressive disorder (MDD) is associated with structural anomalies:
- orbitofrontal cortex and hippocampus are smaller
- lateral ventricles are larger
- by using an MRI we can figure out how these treatments work
- MRIs cannot be used to diagnose disorders by itself
how (fMRI):
- neurons use glucose + oxygen
- after blood delivers oxygen it becomes deoxygenated
- Oxygenated and deoxygenated blood have different magnetic properties which can be measured
- If you measure blood oxy/deoxy ratio in a given area, you’ll have a correlate of neuronal activity in that area
fMRI for behavior and disorders:
- brain activity differs in different tasks, personality characteristics, and mental health disorders
- fMRIs can help us see if certain concepts are involved in an area
con for fMRI
- there are many areas in the brain for many roles
- cannot infer a single cognitive process for it
fMRI: how good is the temporal res and spatial res?
Great spatial resolution (great for studying brain structure)
* Best out of techniques we have covered today
* Can be ‘paired’ w/other techniques (e.g. PET)
Decent temporal resolution
* Better than PET (arguably), not as good as EEG or MEG
* Lag of seconds between activity and signal is still evident
- Popular technique for cognitive neuroscience, but should be interpreted with care
4 brain technique: lesion studies
what, examples, cons
what: a brain lesion can be associated with deficits in behaviours.
examples:
- Patient HM – Removal of Hippocampus + adjoining areas to cure epilepsy; Impaired declarative memories
- Phineas Gage – Lesion of Frontal Lobe; Impulsivity + Impaired Social Behavior
Cons:
* Lesions rarely specific (many brain areas involved)
- like HM had many areas removed not just the hippocampus
- Other behaviors could be impaired but not measured
- we cant measure all variables, so there may be more impairments that we don’t know
- Cases are very rare (often N = 1)
- Is it repeatable? Or was it chance?
- Difficult to make a conclusive argument based on them
- Not experimental, no control for other variables (e.g. individual differences, life history)
what is sensation
receiving, collecting and amplifying information from the environment (initial phase; involves sensory organs)
- taking in the stimuli
- information processing
what is perception
interpreting/organizing this information so that we may understand + react to it (later phase)
- higher order brain stems
- output is response
- automatic judgments that are made without your consent
what are sensory organs
organs that contain specialized receptors attached to neurons, these neurons send signals to the brain
what are the 5 structures of the sensory network
1. Sensory organ
2. Sensory receptors, which are linked to neurons
3. Sensory nerve
4. Thalamus*
5. Specific cortical areas
what are the 5 elements in the vision network (brain to eye pathway)
- Eye
- Photoreceptors
- Optic nerve
- Thalamus (Lateral Geniculate)
- Occipital (or Visual) cortex
what is vision
processing the stimulus of light
what are rods and cones in the eye
Rods
* Dense in periphery
* useful in dim light/darkness
* less involved in color
Cones
* Dense in the fovea
* operate in bright light
* role in color perception
what colors do the three types of cones associate with? what was an earlier thought about colors and cones?
different types of cones respond to different types of light
Max color processing:
- S cone: blue light
- M cone: green/yellow
- L cone: yellow orange
- earlier people thought: if we saw red light we would use the L cone than the others.
what is the trichromatic color theory?
what is another name for it?
- Also called Young-Helmholtz Theory
- Every color is a combination of three independent color
signals (and perhaps the activity of three cones) - Analogy: Color Slider in Imaging Software
what is the opponent process color theory?
Processing of signals in pairs, contrasting color signals interact (Blue v. Yellow, Red v. Green, Black v. White)
what is spectral sensitivity
perception of the brightness of a color
what is contrast enhacement
edges are exaggerated
what is color constancy
there are adjustments in the lighting so we may see colors differently
how do we hear?
what does amplitude and frequency indicate?
- Pressure vibrations in the air
- amplitude: The magnitude of air pressure (in molecule density)
- Related to loudness
- Changes in air pressure (from high to
low) are cyclic (they repeat over time) - frequency (Hz): The amount of cycles per second
- Related to pitch
what is the hearing pathway?
Eardrum > Ossicles > Cochlea > Hair Cells > Vestibulocochlear Nerve > Thalamus (Medial Geniculate) > Auditory/Temporal Cortex