L4- Recognition of viruses by the innate immune system Flashcards
1
Q
How do immune cells sense viruses?
A
Slides 3-5
2
Q
What are PRRs? What do virus-sensing PRRs recognise?
A
Slide 6-9
3
Q
What is a key regulator of immune responses to virus infection? What type of responses does it cause?
A
Type I interferon responses can lead to antiviral immunity, autoimmunity and cancer
Slides 13-18
4
Q
How can PRRs distinguish between the nucleic acid content of a healthy vs virus infected cell?
A
Slide 20-32
5
Q
Which signalling pathways induce type I IFNs in SARS-CoV2-infected cells?
A
Slide 39-51
6
Q
What is the red queen hypothesis?
A
Slide 52-53
