L4: Acid Base Physiology Flashcards
What is the Henderson-Hasselbalch equation?
pH = 6.1 + log (HCO3- / 0.03 x PCO2 )
Phosphate buffer equation (base)
NaOH + NaH2PO4 -> H2O + Na2HPO4
Phosphate buffer equation (acid)
HCl + Na2HPO4 -> NaCl + NaH2PO4
Bicarbonate buffer equation
CO2 + H2O -(carbonic anhydrase) -> H2CO3 -> H+ + HCO3-
pK of bicarbonate buffer
6.1
pK of phosphate buffer
6.8
Secretion of H+ at renal tubules
Draw out diagram
Active secretion of H+
Draw out diagram
Addition of HCO3-
Draw out diagram (Phosphate and Ammonia)
Renal compensation for respiratory acidosis
Increased addition/absorption of HCO3- in kidneys
Respiratory compensation for metabolic acidosis
Increase ventilation to decrease PCO2
Respiratory compensation for metabolic alkalosis
Decreased ventilation to increase PCO2