L2: Body Fluid Compartments & Water Transport Flashcards

1
Q

Total Body Water (TBW) of Men

A

60% of body weight

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2
Q

Total Body Water (TBW) of Women

A

50% of body weight

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3
Q

ICF

A

60% of TBW

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4
Q

ECF

A

40% of TBW

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5
Q

What does the ECF consist of?

A
  • Interstitial fluid
  • Plasma
  • Transcellular flluid
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6
Q

Interstitial fluid is ___% of ___ fluid

A

75% of ECF

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7
Q

Plasma volume is ___% of ___ fluid

A

20% of ECF

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8
Q

Transcellular fluid is ___% of ____ fluid

A

5% of ECF

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9
Q

Blood volume =

A

PV/(1 - Hct)

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10
Q

Composition of Interstitial fluid (avg 13L)

A

Bulk IF (8L)
Bone (2L)
Dense connective tissue (3L)

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11
Q

Avg osmolality of all body fluids

A

290 mOsm

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12
Q

Men Hct

A

45%

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13
Q

Women Hct

A

40%

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14
Q

Average Blood Volume for 70kg male

A
BV = PV/(1 - Hct)
PV = 70*0.6*0.4*0.2 = 3L
BV = 3/(1 - 0.45) = 5.45L
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15
Q

ICF [Na+]

A

15mM

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16
Q

ICF [K+]

A

120mM

17
Q

ICF [Cl-]

A

20mM

18
Q

ICF [Protein]

A

4mM

19
Q

IF [Na+]

A

145mM

20
Q

IF [K+]

A

4.5mM

21
Q

IF [Cl-]

A

116mM

22
Q

IF [Protein]

A

0mM

23
Q

Blood plasma ion concs

A

Similar to IF

24
Q

Major difference between plasma and IF

A

absence of plasma proteins from interstitium

25
Q

Gain =

A

Correction / Error

26
Q

If a diatomic molecule dissociates then how many osmols are produced from 1 mole of the molecule?

A

2 osmols

27
Q

Isosmotic solution causes

A

no change in cell volume

28
Q

hypotonic solution causes

A

cell swelling

29
Q

hypertonic solution causes

A

cell shrinkage

30
Q

how much energy goes into maintaining resting ion gradients?

A

30%