L35: Mechanics Of Breathing Flashcards

1
Q

What are the accessory muscles used on respiration during exercise?

A

Scalenes and SCM

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2
Q

What nerves fire to stimulate inspiration?

A

Phrenic and intercostal nerves

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3
Q

What happens to pressure and air flow when the diaphragm contracts?

A

The diaphragm contracts and descends, increasing the volume of the thoracic cavity. The lungs must follow this and expand. This results in a decrease in intra-alveolar pressure and air flows down its concentration gradient into the lungs.

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4
Q

What 3 pressures are involved in respiration?

A

Atmospheric, intra-alveolar, and intra-pleural

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5
Q

When does atmospheric pressure decrease?

A

Increased altitude

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6
Q

What is the equation for transmural pressure?

A

Transmural pressure= alveolar pressure- intrapleural pressure

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7
Q

Which is always greater, intra-alveolar pressure or intrapleural pressure?

A

Intra-alveolar pressure

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8
Q

What is responsible for the fact that the lung is always stretched to some degree, even during respiration?

A

Transmural pressure gradient

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9
Q

What does more elastic tissue mean for compliance?

A

Compliance is decreased

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10
Q

The slopes on the V/P pressure loops for inspiration and expiration are different. What do you call this?

A

Hysteresis

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11
Q

Why are the slopes for inspiration an expiration different on the P/V loop?

A

The slope gives the compliance of the isolated lung and compliance is different with inspiration and expiration

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12
Q

When is compliance generally measured?

A

During expiration

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13
Q

Normally, the intrapleural pressure has *** pressure?

A

Negative (less pressure in intrapleural than atmosphere)

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14
Q

What creates the negative intrapleural pressure?

A

The two opposing elastic forces of the lungs and the chest wall pulling in opposite directions

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15
Q

What is emphysema?

A

An obstructive lung disease that involves loss of elastic fibers in the lungs secondary to increased protease and elastases

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16
Q

Does compliance increase or decrease in emphysema?

A

Increase (loss of elastic fibers) and therefore the slope of the P/V loop increases

17
Q

What is lung fibrosis?

A

A restrictive lung disease that results in the stiffening of the lung tissues

18
Q

Does compliance increase or decrease with lung fibrosis?

A

Decrease. Therefore slope decreases.

-Collapsing pressure increases