L3.1 Tools to Evaluate protein-ligand Interaction Flashcards

1
Q

3.0. Review
Terminology
A

A
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2
Q

3.0. Review
Terminology
B

A
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3
Q

3.0. Review
Terminology
C

A
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4
Q

3.0. Review
Terminology
D

A
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5
Q

3.0. Review
Terminology

A
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6
Q
  1. Name all tools
A
  1. Structure activity relationship (SAR)
  2. Target Engagement in cellulo
  3. Target Engagement in vitro
    3.4 Mass spectrometry (MS)
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7
Q

3.1. SAR

A
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8
Q

3.2. Target Engagement in cellulo
Name all

A
  • Western Blot
  • Bioluminescence Resonance Energy Transfer (BRET)
  • Celullar Thermal Shift Assay (CETSA)
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9
Q

3.2. Target Engagement in Cellulo
Western Blot

A
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10
Q

3.2. Target Engagement in Cellulo
BRET

A
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11
Q

3.2. Target Engagement in Cellulo
CETSA

A
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12
Q

3.3. Target Engagement in Vitro
Name all

A
  • Fluorescence Anisotropy (FA)
  • Polarization (FP)
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13
Q

3.3. Target Engagement in Vitro
FA

A
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14
Q

3.3. Target Engagement in Vitro
FP

A
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