L30 Osseous regeneration Flashcards
Perio regeneration order
Repair
Regeneration
Reattachment
New attachment
Factors affecting outcome of regeneration
Defect type
Material used
Patient dependent factors (smoking)
Principles behind GTR
Prevent epithelial migration
Space maintenance
Protect slow growing cells
Healing time after GTR
At least 6 weeks but more like 3-6 months
GTRs
Non resorbable ePTFE (Goretex) Resorbable -PLA/PGA -Collagen -Calcium Sulfate
Degradation of PLA/PGA
4-6 weeks
Osteogenesis
Osteoinduction
Osteoconduction
Genesis: viable cells: Auto
Induction: uncommitted CT cells: Allograft
Conduction: non viable scaffold: Alloplast/xenograft
Type of flap/incision when doing regenerative therpy
Sulcular incision
Emdogain
Enamel Matrix Derivative
Forms extracellular matrix on ROOT to promote mesenchymal cells and inhibit epithelial adhesion
Attachment dependent on these cells
Osteoblasts
Fibroblasts
Cementoblasts
GEM 21S
Human platelet derived growth factor
Stiulates migration and proliferation of Osteoblasts fibroblasts, cementoblasts
Biological mediators
Enamel matrix proteins
rhBMP: Recombinant human bone morphogenetic protein
Most predictable furcation in tissue regeneration
Deep class 2 in mandibular or buccal maxillary
Class I
Class II
Class III
I: SRP, flap debride, osseous surgery
II: GTR, osseous surgery
III: tunneling, extraction