L3- HIV vaccine approaches Flashcards
1
Q
What should a vaccine be/do?
A
Slide 3
2
Q
What are some vaccine-induced effector mechanisms?
A
Slide 4
3
Q
What are some cytotoxic T cell vaccine approaches? What is the rationale behind them? Why are they challenging?
A
Slide 5-8
4
Q
What are some antibody-based vaccine approaches? What is the rationale behind them? What is a good target?
A
Slide 9-16
5
Q
How does Env evade antibodies?
A
Slide 17-21
6
Q
What are broadly neutralising antibodies? What are the epitopes they recognise?
A
Slide 22-26
7
Q
How successful have the antibody-based vaccine approaches been?
A
Slide 27-31
