L3- Drug info resources and lit search stats Flashcards
Formal Drug info settings
Hospital pharmacies
Community pharmacies
Ambulatory clinics
Managed care
Pharmaceutical industry
Public health
Informal drug info settings
Gym
Dinner table
Places of worship
off-duty
Anywhere friends/family/coworkers can reach you
Considerations for drug info requests
Type of request:
-patient-specific
-broad request
-recent news
Identity of requestor
-pharmacist
-physician
-nurse
-patient
Tertiary resources
Info that has been summarized to provide an overview of a topic
Ex:
Textbook
Guidelines
Review articles
Internet websites
Lexidrug, mixromedex, etc
Tertiary benefits and limitation
Benefit:
-Comprehensive information from a variety of sources
-Citations to primary and secondary sources
-Fast, easier to use
Limitations:
-Older, less current info
-Not sure if authors looked at “the right sources”
-Bias/lack of expertise
Secondary Resources
Databases that can be used to find primary/tertiary resources via indexing or abstracting
Ex:
-PubMed
-Cochrane Library
-Google scholar
-IPA
-EMBASE
Indexing
Providing citation information
Abstracting
Providing the citation and a brief description (abstract)
Secondary benefits/limitations
Benefits:
-Easily accessible
-Directs to primary literature
Limitations:
-Index terms
-Varying search terminology
-Cost
Secondary Resources
Search Terminology:
-Medical Subject Headings (MeSH)
-United States Adopted Name (USAN)
-International Classification of Disease (ICD)
Additional search tools
-Limits
-Filters
Boolean operators
-DVT AND (or) NOT pulmonary embolism
Primary Resources
Clinical research studies and reports (published or unpublished)
Ex:
-Controlled trials
-Cohort studies
-Case series
-Case reports
Primary resources benefits/limitations
Benefits:
-Detailed info regarding methods
-Can personally assess quality information
-Contains most recent information
Limitations:
-Potentially misleading conclusions
-Requires skilled expertise in literature evaluation
-Time insensitive
Where to look up general drug info
Facts and comparisons, LexiDrug, and MicroMedex
Where to find Compounding info
Trissel’s stability of compounded formulations (through LexiDrug and Mixromedex)
-US Pharmacopeia National Formulary (USP-NF)
-International Journal of Pharmaceutical Compounding
Package insert
DailyMed
-Contain info on FDA approved uses (no off label)
Dosing and administration
Black box warnings
Drug interactions
Pharmacokinetics/pharmacodynamics