L21-The Integumentary system - Skin [2013.10.25] Flashcards
How many layers are epidermis composed of?
Five layers
Name the layers of epidermis from the outermost to the innermost
Stratum corneum Stratum lucidum Stratum granulosum Stratum spinosum Stratum basale
What part of epidermis is present in thick skin but not in thin skin?
Stratum lucidum
What type of cancer develops in stratum basale?
Basal cell carcinoma
What type of cancer develop in stratum spinosum?
Squamous cell carcinoma
Name the cell types present in the epidermis
Keratinocyte
Melanocyte
Langerhans cells
Merkel’s cell
Where is the melanocyte located in the epidermis?
Stratum basale
Where is the Langerhans cells located in the epidermis?
Found in all layers of epidermis but more on Stratum spinosum and BV in papillary dermis
Where are Merkel’s cell located in the epidermis?
Stratum basale
What is the raw materials used in melanine (brown pigment) production?
Tyrosine
What determine the colour of our skin?
The amount of melanine granules
Number of melanocytes are essentially the same in all races
What is the reason for hairs turning grey?
Reduction in number of melanocyte hence the amount of melanine granule produced
What is Vitiligo?
Patches of white area due to lack of melanocyte destroyed by the autoimmune response
What is the shape of the granule of Langerhans Cells?
Cigar shaped
What is the function of Merkel cell?
Touch receptor