L20 chemotherapy Flashcards
1
Q
what inhibitors can be used at each stage of the cell cycle?
A
g0-g1= microtubule inhibitors, topoisomerase inhibitors, alkylating agents
s= topoisomerase inhibitors, anti-metabolites
g2= platinum analogues
m= microtubule inhibitors
2
Q
the idea that using chemotherapy in quick succession is known as what hypothesis?
A
Norton-Simon hypothesis
3
Q
what are common chemo toxicity effects on dividing cells?
A
mucositis
alopecia
diarrhoea
4
Q
what are some common non replicative toxicity effects?
A
nausea, vomitting
neuropathy
