L20-21 Pain Management Flashcards

1
Q

most challenging pain to treat

A

neuropathic pain

- relative resistance to opioids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

cancer pain is usually acute/chronic?

A

chronic

  • hard to manage at end of life
  • progressively more symptomatic, req bg pain control
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

most widely used non-opioids

A

paracetamol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

use of codeine in renal/hepatic impairment

A

try to steer away

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

which opiate least potential for abuse

A

tramadol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

nociceptors

A

specialised neural receptors in the brain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

small myelinated A-delta fibers carry signals for

A

mechanical and thermal stimuli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

C fibers carry signals for

A

all 3 (mechanical, thermal, chemical) stimuli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

nociceptive somatic pain

A
  • site is tender
  • pain is localised to injury site
  • constant and sometimes throbbing or aching, stabbing or pressure
  • skin, muscle, bone
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

where does nociceptive visceral pain originate from?

A

viscera, mediated by stretch receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

nociceptice viscera pain

A
  • poorly localised, referred to a distant cutaneous site which may be tender
  • deep, dull, cramping, gnawing
  • organ or viscera
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

neuropathic pain

A
  • burning, squeezing, tingling, shooting, electric/shocking pain, sharp
  • no area of tenderness or area of exquisite sensitivity to normal innoculus stimuli
  • resistant to opioids
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

tapentadol

A

new, not meant for chronic cancer pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

why is aspirin generally avoided?

A

irreversible antiplatelet effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

NSAIDs precautions

A
  • elderly: >65yo
  • bleeding disorder
  • asthma, bronchospasm
  • gi diseases (ulcer, bleeding)
  • cv disease
  • renal or hepatic dysfunction
  • receiving anticoagulants
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

NSAIDs side effects

A
  • GI
  • reversible platelet inhibition
  • renal effects: edema, htn, renal failure
  • cns: headache, dizziness, nervousness and visual disturbance
  • cv effects: edema, cv accident, htn, MI
  • hypersensitivity rxn
  • hematological: hemolytic anemia, pancytopenia, thrombocytopenia
17
Q

pentazocin

A

agonist at kappa, antagonist at mu

- not available in sg

18
Q

which side effect of codeine gets better?

A

drowsiness

- constipation gets worse

19
Q

adm of morphine w food may

A

increase F, 35% after high fat meal

20
Q

is morphine or fentanyl more potent?

A

fentanyl, approx 100x

21
Q

fentanyl onset of action

A

v fast
- im: 7-15min
- iv: almost immediate
(highly lipophilic)

22
Q

TD fentanyl indicated for pt w

A
  • intolerable undesirable SE from morphine
  • renal failure
  • dysphagia
  • tablet phobia or poor oral compliance