L18 Principles of Cancer Treatment Flashcards

1
Q

aromatase inhibitors: reversible or not?

A

letrozole, anastrozole: reversible competitive inhibitors

exemestane: irreversible

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2
Q

targeted therapy drugs are often cytostatic/cytotoxic

A

cytostatic

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3
Q

solid tumours vs hematological malignancies: which has shorter TD?

A

hematological malignancies

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4
Q

is radiation therapy tumour specific?

A

dose-limiting factor:

  • early effects to rapidly dividing tissues
  • late effects in organs
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5
Q

solid tumours TD

A

2-3 months

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6
Q

hematological malignancies TD

A

24h

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7
Q

pancytopenia

A

lower-than-normal number of red and white blood cells and platelets in the blood

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