L2 what is Pharmacology Flashcards

1
Q

Pharmacodynamics

A

what the drug does to the body

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2
Q

Pharmacokinetics

A

what the body does to the drug

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3
Q

Pharmacokinetics A.D.M.E

A

A-absorption (How does it get in)
D-distribution (Where does it go)
M-metabolism (How is it broken down)
E-excretion (How does it leave)

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4
Q

Potency

A

the strength of something such as a drug or alcoholic beverage.

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5
Q

Efficacy

A

the ability to produce a desired or intended result

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6
Q

Potency vs Efficacy

A

potency: amount of drug necessary to produce desired effect
efficacy: ability of drug to achieve desired effect

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7
Q

Drug selectivity

A

a drug is selective if it affects only one type of cell or tissue and produces a specific physiologic response

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8
Q

Adverse side effects

A

Harmful or undesirable effect of a medication or intervention

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9
Q

Concentration response

A

Relationship exists between the concentration of a drug at its site of action and its therapeutic or toxic effects.

Just because a drug is in the system doesn’t mean it’s enough to be therapeutic– drug level needs to reach a certain concentration to be therapeutic

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10
Q

dose response

A

correlation between the amount of a drug given and its effects

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11
Q

Drug half life

A

the time required for the elimination process to reduce the concentration of the drug to 50% what it was at initial administration

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12
Q

Drug Agonist

A

a drug that will bind to a receptor on a cell and trigger a response by the cell, generally mimicking the response or action of a naturally occurring substance

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13
Q

Drug Antagonist

A

a drug that blocks another drug from combining with a receptor

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14
Q

Therapeutic Index

A

A ration of the blood concentration at which a drug causes death (in animal) or toxicity (human) to the amount that causes a therapeutic effect.

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15
Q

Drug target

A
  • Receptors
  • Ion channels
  • Enzymes
  • Carrier Molecules
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