L2: Surfactants Flashcards
Are surfactants soluble, in what?
Organic solvent
Water
What are surface active agents or surfactants
Molecules and ions that are ADSORBED at interfaces.
Surfactants contain both hydrophobic and hydrophilic groups, t or f?
TRUEE.
What could the hydrophilic regions of a surfactant be?
Anionic
Cationic
Zwitterionic
Non ionic
What are the hydrophobic regions in a surfactant?
Saturated or unsaturated hydrocarbons chains.
Heterocyclic or aromatic rings.
Why are anionic surfactants not suitable for oral dosage forms
Unpleasant taste, gut irritation.
Name an example of a anionic surfactant
Sodium lauryl sulfate BP
Pharmaceutical use of anionic surfactants
Preoperative skin cleaner, due to its bacteriostatic action against gram positive bacteria.
And medicated shampoos
Pharmaceutical use of Cationic surfactants
Solutions used to clean wounds and skin,
Store sterilised surgical instruments
Example of Cationic surfactant
Cetrimide
Domiphem bromide
What is a zwitterionic surfactant.
Known as ‘internal salt’
Has an anion and cation in one molecule chemically joined together.
Pharmaceutical use of zwitterionic surfactants
Fairly limited
In skin care products as mild detergents.