L2: Surfactants Flashcards

0
Q

Are surfactants soluble, in what?

A

Organic solvent

Water

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1
Q

What are surface active agents or surfactants

A

Molecules and ions that are ADSORBED at interfaces.

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2
Q

Surfactants contain both hydrophobic and hydrophilic groups, t or f?

A

TRUEE.

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3
Q

What could the hydrophilic regions of a surfactant be?

A

Anionic
Cationic
Zwitterionic
Non ionic

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4
Q

What are the hydrophobic regions in a surfactant?

A

Saturated or unsaturated hydrocarbons chains.

Heterocyclic or aromatic rings.

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5
Q

Why are anionic surfactants not suitable for oral dosage forms

A

Unpleasant taste, gut irritation.

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6
Q

Name an example of a anionic surfactant

A

Sodium lauryl sulfate BP

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7
Q

Pharmaceutical use of anionic surfactants

A

Preoperative skin cleaner, due to its bacteriostatic action against gram positive bacteria.

And medicated shampoos

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8
Q

Pharmaceutical use of Cationic surfactants

A

Solutions used to clean wounds and skin,

Store sterilised surgical instruments

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9
Q

Example of Cationic surfactant

A

Cetrimide

Domiphem bromide

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10
Q

What is a zwitterionic surfactant.

A

Known as ‘internal salt’

Has an anion and cation in one molecule chemically joined together.

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11
Q

Pharmaceutical use of zwitterionic surfactants

A

Fairly limited

In skin care products as mild detergents.

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