L2-Human Genome

Question 1

How many base pairs is cM? What is 1% recombination?

Answer 1

1 million bp’s…1% recombination is 1 million bp (1cM)

Question 2

How many bp are in the human genome?

Answer 2

about 6 billion

Question 3

How many genes in the human genome?

Answer 3

22,000 genes

Question 4

How many bp is the avg gene?

Answer 4

14k

Question 5

What is the physical position of a gene on a chromosome?

Answer 5

Locus

Question 6

What are alternative forms a a gene that can exist at a given locus?

Answer 6

Allele

Question 7

What is the # of copies of particular gene in the genome?

Answer 7

Dosage

Question 8

What is it when a locus has at least 2 relatively common alleles with a frequency of 1% or greater?

Answer 8

Polymorphism

Question 9

What is the sequence of DNA required for production of a final product?

Answer 9

a gene!

Question 10

A ________ transcript produces most rRNA molecules.

Answer 10

Polycistronic

Question 11

How much of the human genome is unique, how much is repetitive? What are the two types of repetitive DNA?

Answer 11

50/50-Dispersed and Satellite

Question 12

If 420 mutations have been found for the PAH allele, how many PAH alleles are there?

Answer 12

421…1 Wild Type+420 mutations