L14 The Hypothalamus + Autonomic Control Flashcards

1
Q

How many major nucleis does the Hypothalamus have?

A

11

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2
Q

What is the role of the hypothalamus?

A

It’s primary role is to maintain homeostasis, which is the body’s ability to keep its internal environment stable

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3
Q

Briefly describe how homeostasis works (5)

A

1) Disruption to a vital parameter
2) Sensory inputs (varied)
3) Integration by hypothalamus
4) Activates autonomic NS/ Neuroendocrine/ Behavioural
5) Restoration of vital parameter within physiolgical range

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4
Q

What are the major nucleis of the hypothalamus (that we need to know)?

A
  • Paraventricular nucleus
  • Supraoptic nucleus
  • Anterior Pituitary (Adenohypophysis)
  • Posterior Pituitary (Neurohypophysis)
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5
Q

How are troph cells stimulated in the adenohypophysis?

A

Troph cells stimulated by releasing hormones from parvocellular neurons of the hypothalamus

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6
Q

Where is the origin of magnocellular neurons?

A

These neurons have their cell bodies located in the hypothalamus, primarily within the supraoptic nucleus (SON) and the paraventricular nucleus (PVN)

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7
Q

How does the neurohypophysis regulate essential body functions related to social behaviour and reproduction?

A

It releases hormones from the magnocellular neurons directly into systemic cirulcation

Magnocellular neurons release oxtocin and vasopressin

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8
Q

What are the major pituitary hormones?

A
  • Tropic hormones

(Neurohypophysis)
- ADH/ vasopressin: Fluid balance
- Oxytocin: Parturition and lactation

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9
Q

Is the autonomic nervous system (ANS) voluntary?

A

No, its involuntary

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10
Q

What are the two efferent pathways of the ANS?

A

Sympathetic and parasympathetic

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11
Q

What are the innervate effectors (muscles/glands that sends signals through nerves) for ANS?

A

Smooth muscle
Cardiac muscle
Glands

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12
Q

Why can’t the ANS function without the hypothalamus?

A

The hypothalamus acts as a central control center, integrating information from various parts of the brain and body

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13
Q

Which of the following requires greater input from the hypothalamus?

A) Pupillary constriction/dilation
B) Salivation
C) Regulation of body temperature

A

C) Regulation of body temperature requires the greatest input from the hypothalamus.

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14
Q

What are the anatomical organisations of ANS?

A

The ANS uses a two neuron chain to connext the central nervous system (CNS) to target organs

Preganglionic neuron: CNS (brain or spinal cord)
Postganglionic neuron: (Sympathetic and parasympathetic ganglia)

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15
Q

Why is the IML Cell column T1-L3 important?

IML= Intermediolateral

A

It’s crucial because it contains the cell bodies of the preganglionic neurons of the sympathetic nervous system. These neurons are responsible for initiating the ‘fight or flight’ response

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16
Q

What is a sympathetic chain?

A

They consists of two chains of itnerconnected ganglia (clusters of nerve cell bodies)

17
Q

What controls the sympathetic preganglionic neurons?

A

Ventrolateral medulla

18
Q

Where within the spinal cord is the parasympathetic organisation found?

A

Sacral region (lower half)

19
Q

Would you expect a sympathetic chain in the parasympathetic organisation?

A

No, ganglions are alone and not chained

20
Q

What are the two types of cranial parasympathetic organisation?

A
  • Oculomotor nerve (CN III) - originates from midbrain
  • Vagus nerve (CN X) - orginiates from medulla
21
Q

Why is the vagus nerve important?

A

The vagus nerve (cranial nerve X) carries 80% of total parasympathetic outflow

22
Q

Which CNS are the muscarinic receptors found?

A

They are general found in the parasympathetic nervous system.

General found at the synapse between the postganglionic parasympathetic neuron and the target organ.

23
Q

Which CNS are the adrenergic receptors found?

A

Found in sympathetic nervous system

Most postganglionic neurons of the SNS release norepinephrine as their neurotransmitter.