L14: Sensory System: Chemical Senses Flashcards

1
Q

What are the two chemical senses in humans?

A

Taste (gustation) and smell (olfaction).

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2
Q

What evolutionary advantage do chemical senses provide?

A

They help detect chemicals in the environment, find food, identify mates, and avoid harmful substances.

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3
Q

What are the five basic tastes?

A

Sweet, sour, salty, bitter, and umami.

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4
Q

What is umami, and what foods are associated with it?

A

Umami is a savoury taste associated with foods like mushrooms, soy sauce, and meat.

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5
Q

What type of receptors are involved in detecting chemical senses?

A

Chemoreceptors.

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6
Q

How does the taste system work to detect stimuli?

A

Chemicals bind to receptors on taste cells, causing signal transduction, which leads to neural signals sent to the brain.

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7
Q

How are taste buds organised on the tongue?

A

They are distributed across the tongue, with some areas more sensitive to certain tastes, but all areas can detect all basic tastes.

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8
Q

What is the lifespan of taste receptor cells?

A

About two weeks, after which they are replaced by basal cells.

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9
Q

What happens when you have a cold, and how does it affect taste?

A

A blocked nose reduces smell perception, which diminishes the ability to detect flavour since taste and smell combine to create flavour.

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10
Q

What is signal transduction in taste?

A

The process of converting a chemical signal (taste molecule binding) into an electrical signal (neural message).

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11
Q

How do humans detect salty tastes?

A

Sodium ions enter taste cells through non-gated channels, causing depolarization.

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12
Q

How do humans detect sour tastes?

A

Hydrogen ions from acidic substances enter cells and either block potassium channels or depolarize the cell directly.

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13
Q

How are sweet, bitter, and umami tastes detected?

A

Through G-protein-coupled receptors that trigger intracellular signalling cascades.

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14
Q

What is the role of the brain’s primary gustatory cortex?

A

It processes taste information for conscious awareness and flavour perception.

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15
Q

How is smell different from taste in terms of receptor cells?

A

Olfactory receptor cells are neurons and can fire action potentials, while taste receptor cells are not neurons.

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16
Q

Where are olfactory receptors located?

A

In the olfactory epithelium at the roof of the nasal cavity.

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17
Q

What is population coding in smell?

A

The process by which the brain decodes patterns of activity from multiple olfactory neurons to identify specific smells.

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18
Q

Why does smell have a strong association with memory and emotion?

A

Olfactory signals are processed in the limbic system, which is involved in emotions and memory.

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19
Q

What is anosmia?

A

The loss of the sense of smell, which can occur due to damage to olfactory pathways or the brain.

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20
Q

How do the taste and smell pathways differ in the brain?

A

The olfactory pathway bypasses the thalamus initially, while the gustatory pathway does not.

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21
Q

How do taste and smell combine to create flavour?

A

Flavour is the result of both taste and smell information converging in the brain, along with texture and other sensory inputs.

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22
Q

What is the primary purpose of bitterness detection in taste?

A

To help avoid toxic substances, which are often bitter.

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23
Q

What happens to taste cells if damaged by hot or abrasive food?

A

They regenerate, as basal cells produce new taste receptor cells every two weeks.

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24
Q

Why do older individuals often experience a decline in their sense of taste?

A

The rate of taste receptor cell replacement slows down with age.

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25
Q

What are the cranial nerves involved in taste perception?

A

Facial nerve (cranial nerve VII), glossopharyngeal nerve (cranial nerve IX), and vagus nerve (cranial nerve X).

26
Q

What is the role of the thalamus in the gustatory pathway?

A

It serves as a relay station, processing and directing taste signals to the primary gustatory cortex.

27
Q

How does the brain determine the type of food being consumed?

A

By integrating signals from different taste receptors and analysing the relative intensity of sweet, sour, salty, bitter, and umami.

28
Q

What is palatability, and how is it determined?

A

Palatability refers to how pleasant a food tastes, influenced by individual preferences and taste pathways connecting to the hypothalamus.

29
Q

How does smell detection work at the cellular level?

A

Odor molecules bind to specific receptors on olfactory cells, triggering a G-protein-mediated signal transduction pathway that generates action potentials.

30
Q

What unique feature of olfactory receptor neurons allows them to be replaced?

A

Unlike most neurons, olfactory receptor neurons regenerate approximately every 30-60 days.

31
Q

How is smell information processed in the brain?

A

Olfactory signals travel from the olfactory bulb directly to the olfactory cortex and limbic areas, influencing both recognition and emotional responses.

32
Q

What is the significance of the limbic system in olfaction?

A

It connects smells to emotions and memories, explaining why certain smells can trigger vivid recollections or emotional responses.

33
Q

What is the difference between the olfactory and gustatory pathways?

A

Olfactory signals bypass the thalamus initially, whereas gustatory signals pass through the thalamus before reaching the cortex.

34
Q

Why do smells become less noticeable after prolonged exposure?

A

Due to sensory adaptation, where olfactory receptors reduce their response over time when continuously exposed to the same stimulus.

35
Q

How do G-protein-coupled receptors contribute to taste and smell?

A

They mediate signal transduction by triggering intracellular pathways in response to binding with specific chemicals.

36
Q

What is agnosia, and how does it relate to taste and smell?

A

Agnosia is the inability to recognize certain sensory inputs; in taste or smell, it can result from brain damage impairing perception pathways.

37
Q

Why is the idea of a ‘taste map’ on the tongue incorrect?

A

All areas of the tongue can detect all basic tastes; sensitivity varies, but regions are not exclusively dedicated to one taste.

38
Q

What types of chemicals are typically detected by sour taste receptors?

A

Hydrogen ions (H+) from acidic substances.

39
Q

How do olfactory receptors detect a wide range of odours?

A

Each receptor can bind multiple odour molecules, and the brain decodes the pattern of activity from different receptors to identify specific smells.

40
Q

How does signal transduction differ between taste and smell?

A

Taste cells use neurotransmitter-like signals to activate nearby neurons, while olfactory cells generate action potentials directly as they are neurons themselves.

41
Q

What is signal transduction in sensory systems?

A

The process of converting a stimulus (e.g., chemical, light, sound) into an electrical signal that the nervous system can process.

42
Q

What are the two major receptor families involved in taste detection?

A

T1 (Taste 1) receptors for sweet and umami, and T2 (Taste 2) receptors for bitter.

43
Q

How do hydrogen ions (H+) contribute to the sensation of sour taste?

A

They either block potassium channels to prevent repolarization or enter cells directly to cause depolarization.

44
Q

How is saltiness detected in food?

A

By sodium ions (Na+) entering taste cells through non-gated ion channels, leading to depolarization.

45
Q

What role do basal cells play in the gustatory system?

A

They produce new taste receptor cells, enabling continuous renewal of taste detection.

46
Q

What experimental techniques helped identify taste receptor genes?

A

Genetic modification in mice, such as gene knockouts, to observe changes in taste detection.

47
Q

What happens when there is a mutation in a taste receptor gene?

A

It can impair the ability to detect certain tastes, such as sweet or bitter.

48
Q

What is the primary role of the cranial nerves in taste?

A

To transmit taste signals from the tongue and oral cavity to the brain.

49
Q

What is the function of the ventral posterior medial (VPM) nucleus of the thalamus in taste perception?

A

It processes taste signals before relaying them to the primary gustatory cortex.

50
Q

How do texture and other sensations contribute to flavour?

A

They combine with taste and smell information to create the overall perception of flavour.

51
Q

What is population coding in olfaction?

A

A method where the brain interprets patterns of activity from multiple olfactory receptors to identify specific smells.

52
Q

Why is the sense of smell more evolutionarily ancient than taste?

A

It bypasses the thalamus and connects directly to primitive brain regions like the limbic system.

53
Q

How does the brain differentiate between sweet and umami tastes?

A

By using different combinations of T1 receptor subunits specific to each taste.

54
Q

What is the difference between primary and secondary neurons in sensory pathways?

A

Primary neurons detect stimuli and synapse onto secondary neurons, which relay signals to higher brain centres.

55
Q

What is a ‘glomerulus’ in the olfactory bulb?

A

A structure where axons of olfactory receptor neurons with the same receptor type converge.

56
Q

What is the role of the primary olfactory cortex?

A

To process raw smell signals and identify specific odours.

57
Q

Why is the adaptation of smell important?

A

It prevents overstimulation from constant exposure to the same odour, allowing focus on new smells.

58
Q

How can memories and emotions be triggered by smells?

A

Smells are processed in the limbic system, which governs emotion and memory, creating strong associations.

59
Q

What is the evolutionary advantage of combining taste and smell?

A

It enhances the ability to evaluate food for nutritional value or potential danger.

60
Q

What is the significance of olfactory receptor diversity?

A

Thousands of receptor types allow humans to detect a wide range of odours through combinatorial coding.