L13: Fluid, Electrolytes, and Acid-Base Balance Flashcards
what are the characteristics of body fluids that affect cell function(4)?
1) volume (amount)
2) osmolarity (concentration)
3) electrolyte concentration (composition)
4) pH (degree of acidity)
how much total body water is in intracellular fluid (ICF) in adults?
about 2/3
how much total body water is in extracellular fluid (ECF) in adults?
about 1/3
what are the two major divisions of extracellular fluid?
1) intravascular fluid (liquid part of blood-plasma)
2) interstitial fluid (between cells and the outside of blood vessels
what is the minor division of extracellular fluid?
transcellular fluid (cerebrospinal fluid, pleural, peritoneal, and synovial fluids)
fluid that contains a large number of dissolved particles is _________ than the same fluid that contains only a few particles
more concentrated
what is the osmolarity of a fluid?
a measure of the number of particles per kg of water
Can sodium cross easily through cell membranes?
it can but not easily
what sets the tonicity of a fluid?
presence of particles that can not cross easily across cell membranes
what is tonicity?
the effective concentration of a fluid. A measure of how a solution affects the volume and pressure of a cell’s fluid
what is an isotonic fluid?
having equal osmotic pressure or concentration of water and solutes.
e.g. blood
what is a hypertonic solution?
a solution with a higher concentration of solutes than another solution, or than the inside of a cell. Water moves out of the cell into the hypertonic solution, causing the cell to shrink or shrivel
a solution that is more concentrated than blood
what is a hypotonic solution?
a solution that has a lower concentration of solute compared to the cell.
a solution that is more dilute than blood
what is fluid homeostasis?
the dynamic interplay of three processes:
1) fluid intake and absorption
2) fluid distribution
3) fluid output
what is fluid intake?
drinking and eating
what is fluid distribution?
the movement of fluid among its various compartments and between the intracellular and extracellular compartments
how does fluid distribution between intracellular and extracellular compartments occur?
by osmosis
how does fluid distribution between vascular and interstitial portions of the ECF occur?
by filtration
what are examples of fluid output?
urine and sweat
to maintain homeostasis, intake and output have to be…
equal to each other
how much is the average fluid intake via eating and drinking?
2300mL for healthy adults
describe thirst(2)
1) the conscious desire for water, regulates fluid intake when plasma osmolarity increases
2) thirst-control mechanism is located in the hypothalamus
what are osmoreceptors?
receptors that continuously monitor plasma osmolarity. when it increases, they cause thirst by stimulating neurons in the hypothalamus
osmoreceptors-mediated thirst
baroreceptor-mediated thirst
Changes in arterial blood pressure, sensed by arterial baroreceptors, influence drinking behavior. Decreases in ABP stimulate fluid intake, an effect that appears to be mediated entirely via arterial baroreceptor-evoked renin secretion with the resulting increase in blood levels of angiotensin II acting on the brain to stimulate drinking
Angiotensin II- and III-mediated thirst
refers to the physiological mechanism where the hormones angiotensin II and, to a lesser extent, angiotensin III, directly stimulate the sensation of thirst by acting on specific receptors in the brain, primarily within the subfornical organ (SFO), leading to an increased urge to drink water when the body detects low blood volume or dehydration
what is angiotensin II’s role in the thirst response?
binds to the hypothalmus in the brain, stimulating thirst
describe the relationship between hormones and the kidneys when it comes to fluid output
the kidneys respond to some hormones that influence urine production
which hormones influence urine production in the kidneys(3)?
1) antidiuretic hormone (ADH)
2) renin-angiotensin-aldosterone mechanism
3) atrial natriuretic peptides (ANPs)
what are the avenues of fluid output(4)?
1) kidneys
2) skin
3) lungs
4) GI tract
what is insensible fluid output?
fluid output that is not visible
1) skin (sweat)
2) lungs
what is sensible fluid output?
visible fluid output
1) kidneys
2) GI tract
how much fluid moves into the GI tract then returns to the ECF?
3 - 6 L
the average adults excretes how much fluid each day through feces?
100mL
what are S/Sx of clinical dehydration(2)?
1) ECV deficit
2) hypernatremia
what is another name for ADH?
vasopressin
- A patient is diaphoretic and has an oral temperature of 104° F. These are classic signs of:
A. ADH deficit.
B. extracellular fluid loss.
C. insensible water loss.
D. sensible water loss.
C
Fluid and Electrolytes for Nursing Students YouTube Videos
https://www.youtube.com/watch?v=7piicQkfauk
https://www.youtube.com/watch?v=Xdf7jutmSvg
what are normal sodium (Na+) lab values?
136-145mEq/L
what are normal potassium (K+) lab values?
3.5-5.0 mEq/L
what are normal chloride (Cl-) lab values?
98-106 mEq/L
what are normal total CO2 lab values?
22-30 mEq/L
what are normal bicarbonate (HCO3) lab values?
arterial: 21-28 mEq/L
venous: 24-30 mEq/L
what are normal total calcium (Ca2+) lab values?
9-10.5 mg/dL