L11: Mood Instability Flashcards

1
Q

Define mood instability

A

rapid oscillations of intense affect, with a difficulty in regulating these oscilattions or their behavioural consequences

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2
Q

What are the characteristics of a depressive episode?

A
  • low mood
  • loss of enjoyment (anhedonia)
  • loss of interest & motivation for everyday activities
  • sleep problems
  • appetite problems
  • loss of concentration
  • poor energy
  • psychomotor agitation/retardation
  • feelings of emptiness or worthlessness
  • self doubt/blame
  • suicidal thoughts
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3
Q

What are the characteristics of (hypo)mania?

A
  • constant elation or euphoria
  • irritable mood, getting into arguments easily
  • observable hyperactivity
  • increased energies
  • inappropriate optimism
  • overestimating personal ability
  • poor judgment, grandiose plans
  • speeding up of thought and speech, flights of ideas
  • need for little sleep
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4
Q

What is the time course of bipolar disorder?

A
  • switching episodes of mania vs depression in varying severity
  • can also have mixed states
  • and in between “euthymic” states
  • looks very different for every person
  • around 50-60% relapsing within a year of recovery from a mood episode
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5
Q

What are other common symptoms in bipolar disorder?

comorbidity & differential diagnosis

A
  • 30-70% report anxiety
  • 93% anxiety disorder lifetime comorbidity
  • 75% psychotic symptoms (at either episode)
    important differential diagnosis
  • MDD
  • schizoaffective disorder & psychotic disorder
  • anxiety disorder
  • substance use disorder
  • personality disorder
  • ADHD (in children)
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6
Q

What do you know about the epidemiology of bipolar disorder?

A
  • around 2-4% of pop
  • bipolar I affects men & women equally
  • bipolar II more women (hypomania)
  • strong genetic component
  • high risk of suicide (30-50% attempts, of which 15-20% complete)
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7
Q

What is the developmental trajectory of BD?

A

for most
- starts before age of 21
- starts w single depressive episode
- family history of BD
into young adulthood:
- becomes recurrent depression and prodomal hypomania symptoms present throughout young adulthood
- then mania or hypomania episode comes

this is also referred to as the bipolar spectrum (how it develops over time)

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8
Q

What is typically the treatment for bipolar disorder?

A
  • in acute phase: medication but need to be careful here
  • psychosocial interventions
  • challenge of treating anxiety
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9
Q

Is there a link between bipolar disorder & creativity?

A
  • correlational evidence between creativity & bipolar
  • first degree relatives of BD more likely to have creative/high achieving professions
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10
Q

In what other disorders does mood instability present?

A

part of diagnostic symptoms in BPD & partly ADHD and PTSD
recent studies
- over half ppl w depression & ADs
- generally ppl w mental disorder have higher chance of mood instabiltiy
-> TRANSDIAGNOSTIC PHENOMENON

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11
Q

In the general pop, is there a developmental specificity to mood instablity?

A

adolescents more mood instability

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12
Q

Why is mood instability so clinically relevant?

A

its associated w
- general poor clinical outcomes
-suicidal thinking
- healthcare service use
- self harm
- addiction
- trauma
-> GENERAL POOR PROGNOSIS

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13
Q

Are there any abnormalities in cognitive functioning that are associated w mood instability?

A
  • biases in processing emotional info (negative memory biases) in BD
  • attentional dysfunction in ADHD w hypomanic symptoms
  • dysfunctional mental imagery
    -> both a bit confusing research
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14
Q

How do we usually measure mood instability?

A
  • self report scales of trait constructs
  • weekly (or longer) retrospective ratings of symptoms (but memory biases)
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15
Q

How could we improve how we capture mood instability?

A

combination of maths & digital tools
like mood tracking applications

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16
Q

How does mental imagery relate to mood instability in bipolar?

A

dysfunctional mental imagery is “emotional amplifier” in between episodes, it amplifies the mood rapidly changing (so positive imagery -> more positive affect etc)
- higher levels of intrusive prospective imagery & more vivid imagery of future negative events
- these higher levels correlated w levels of anxiety & depression in bipolar sample
- intense suicidal flashforwards & positive flashforwards
- feels very real

-> this intenseness of the mental imagery can be seen in general mood instability across mental illnesses (TRANSDIAGNOSTIC)

associated w differential activation in frontal gyrus & insula

17
Q

What are some ways to use imagery to reduce mood instability?

A

imagery rescripting & meta cognitive imagery manipulation can reduce mood instability

18
Q

What is positive mood amplification? why can it be problematic?

A

the process leading to elevated mood
dysregulated positive mood = key feature of (hypo) mania and bipolar disorder which is linked to risk taking, reduced sleep, and socially inappropriate behaviour
so need to target this early mood amplification to avoid future issues

19
Q

What is mental imagery?

A

the experience of perception in the absence of eliciting sensory input

20
Q

What are 2 questions that remain about the relationship between mental imagery & mood instability? How were the 2 questions investigated?

A
  1. does mental imagery also elicit mood amplification if stimulus is not as mood congruent? (stimulus specificity) like does calm mental imagery also elicit positive mood amplification?
    -> compare changes in self reported affect across 2 eliciting stimulus categories (elated vs calm mental imagery generation)
  2. How specific is the effect in terms of affective response? is negative mood also amplified in certain mental imagery conditions or does it only amplify positive moods? (response specificity)
    -> investigate task dependent changes in self reported affect across distinct affect clusters (negative affect, positive calm affect, positive excitiement affect)
21
Q

How is mental imagery’s relationship with mood instability generally measured?

A
  1. imagery generation training
  2. positive (elated) or neutral (calm) picture word cue imagery generation task (got either a positive or neutral word paired with a picture, then asked to generate mental image)
  3. rate vividness of mental imagery
  4. affect measurement (before, during, and after task)
22
Q

What were the results from the mental imagery-mood instability research paper?

A
  • the higher the mood instability, the more the affect changed as a result of mental imagery
  • the more elated the word associated with the picture (stimulus), the faster the affect increased
  • no effect of the positive/neutral mental imagery on negative affect
    -> amount of mood amplification depended on type & content of mental imagery