L11 Cysts of the jaws Flashcards
What is the definition of a cyst?
A pathological cavity having fluid, semi-fluid or gaseous contents which is not created by the accumulation of pus; it is frequently, but not always, lined by epithelium.
Do odontogenic cysts contain epithelium?
Yes, always.
Describe the 3 components of a cyst.
- Capsule: connective tissue and/or granulation tissue, BVs, +/-inflammation, +/- cholesterol, +/- heamosiderin
- Lining: epithelial or not
- Lumen: fluid, semi-fluid or gaseous. Contains serum proteins, tissue products, lining cells +/- inflammatory cells, +/- cholesterol
Cyst lining + capsule = cyst wall
What is the difference between odontogenic and non-odontogenic cysts?
Odontogenic: epithelial lining derived from epithelial residues of the tooth forming organ
Non-odontogenic: epithelial lining, if present, is derived from other sources than the tooth forming organ
What 2 categories are odontogenic cysts divided into?
- Inflammatory
- Developmental
What are the 3 types of inflammatory odontogenic cysts?
- Radicular cysts
- Residual cysts
- Inflammatory collateral cysts (paradental or buccal bifrucation cyst)
Describe radicular cysts.
Most common inflammatory odontogenic cyst, arise from a non-vital tooth usually as a result of caries.
Arises from the epithelial rests of Malassez in the PDL as a consequence of inflammation, usually following pulp necrosis.
Describe residual cysts.
Same as radicular, except the tooth has been extracted and the cyst has remained.
Describe paradental cysts.
Most common inflammatory collateral cyst, usually affects the lower 3rd molars.
Describe buccal bifurcation cysts.
An inflammatory collateral cyst seen in children.
Name the developmental odontogenic cysts.
- Follicular (dentigerous and eruption cysts)
- Odontogenic keratocyst
- Gingival cyst
- Lateral periodontal cyst
- Botryoid odontogenic cyst
- Orthokeratinised odontogenic cyst
- Glandular odontogenic cyst
- Calcifying odontogenic cyst
Which 2 types of developmental odontogenic cysts are most common?
- Odontogenic keratocysts
- Follicular cysts (dentigerous, eruption)
The pathogenesis of jaw cysts require which 3 components?
- A source of epithelium
- Stimulus for proliferation
- Growth and bone resorption
What are the 3 sources of odontogenic epithelium in cyst formation?
- Hertwig’s epithelial root sheath (epithelial rests of Malassez)
- Reduced enamel epithelium
- Dental lamina
Which cysts’ epithelia develop from the epithelial rests of Malassez?
- Radicular cysts
- Residual cysts
Which cysts’ epithelia develop from the reduced enamel epithelium?
- Dentigerous cysts
- Eruption cysts
Which cysts’ epithelia develop from the dental lamina?
- Odontogenic keratocysts
- Gingival cysts
- Lateral periodontal cysts
- Odontogenic tumours
What type of tooth is a radicular cyst always associated with?
A non-vital tooth
What are the 3 main locations of radicular cysts?
- Apical: at the apex of the tooth, associated with the opening of the root canal
- Lateral: at the side of the tooth, associated with a lateral branch of the root canal
- Residual: a radicular cyst which has persisted after extraction of the associated tooth
What age group are radicular cysts most commonly seen in?
Age 31-40
Which teeth are radicular cysts most commonly seen in?
Most common in the maxillary anterior region, particularly the lateral and central incisors.
What are the symptoms of a radicular cyst?
- Many are symptomless and discovered incidentally on radiographs
- Larger cysts present as slowly enlarging swellings
- May present with signs of acute inflammation due to re-infection of cyst
- Non-vital tooth
- Suggestion that some individuals are susceptible to cysts and present with more than 1 cyst
What are the signs of a radicular cyst?
- Usually not many signs
- Larger cysts may present with buccal swellings
- May be palatal swelling, but rarely lingual
- Small cysts can produce bony hard swellings
- Large cysts may be springy with egg shell crackling sound when compressed
- Large cysts may erode the bone and be fluctuant (compressible)
What cyst is shown in these radiographs?
Radicular.
Radicular cysts have corticated borders.
For a radicular cyst, the cyst cavity is continuous with what?
The cyst cavity is continuous with the lamina dura, means the cyst has arisen from the PDL.
Glistening appearance due to cholesterol deposits.
Describe the epithelial lining of radicular cysts.
- Stratified squamous epithelium
- Non-keratanised (somes keratnised if cyst is open to the mouth)
- Varying thickness
- Arcaded appearance due to thin strands of odontogenic epithelium extending into CT
- Mucus cell metaplasia is common, see grey coloured Goblet cells microscopically
- Ciliated epithelium may be seen