L10 New Trends in the Biotech Industry

Question 1

What is the history of biotech evolution?

Answer 1

Slide 3

Question 2

How did biotech evolution start?

Answer 2

DNA cloning
- Slide 4

Question 3

Where were all these technologies discovered?

Answer 3

Slide 7,8
- Kendall Square; in the Lab Central, along with Flagship Ventures

Question 4

How is gene therapy done?

Answer 4

Slide 11

Question 5

What are some gene delivery vehicles?

Answer 5

Slide 12

Question 6

What are the adv of using gene therapy?

Answer 6

Slide 14, 15 (could possibly skip preclinical testing)

Question 7

If you want to develop a drug, what is one way you can get funding/ what kind of drug would be good to develop?

Answer 7

Slide 17

Question 8

What are the current challenges for gene therapy?

Answer 8

Slide 18
- Many genes that can be mutated, restoration of one may not cure the disease

Question 9

What are the challenges of using AAV for gene therapy?

Answer 9

Slide 19

Question 10

What are some challenges for using lentivirus/AAV and lipid nanoparticles that can be solved with EVs?

Answer 10

Slide 21, 22, 23

Question 11

What are the key features to starting a biotech company?

Answer 11

Slide 26