L1 Flashcards
disorders cause dangerous increase in the volume of intracranial contents
- Generalized cerebral edema
- Hydrocephalus
- Hemorrhages
- Ischemia
- Tumors
accumulation of
excess fluid within the brain parenchyma.
Cerebral edema
two types of cerebral edema
• Vasogenic edema
• Cytotoxic edema
integrity of the normal blood- brain barrier is disrupted
fluid to shift from the vascular compartment into the extracellular spaces of the brain.
Vasogenic Edema
Can be localised or generalized
is an increase in intracellular fluid secondary to neuronal and glial cell injury.
• It follow generalized hypoxic- ischemic insult or after exposure to some toxins.
Cytotoxic edema
CSF flows through the……………………. and
……………………into the subarachnoid space, where it is
absorbed by arachnoid granulations.
foramina of Luschka
Magendie
to an increase in the volume of
cerebrospinal fluid (CSF) within the ventricular system most often is a consequence of
• Impaired flow
• Decreased resorption of CSF
Hydrocephalus
Patterns of Hydrocephalus
• Non communicating Hydrocephalus
• Communicating Hydrocephalus.
• A localized obstacle to CSF flow within the
ventricular system causes enlargement of a portion
of the ventricles.
Non communicating Hydrocephalus
Most common is cause of Non communicating Hydrocephalus
masses obstructing
the foramen of Monro or compressing the cerebral aqueduct.
• The entire ventricular system is enlarged
Communicating Hydrocephalus
Common cause Communicating Hydrocephalus
reduced CSF resorption.
sunsetting of the eyes ventricular expansion and
increase intracranial pressure
Hydrocephalus
compensatory increase in CSF volume
(……………………………….) may occur secondary to a loss of brain volume from any underlying cause (e.g., infarction, neurodegenerative disease).
hydrocephalus ex vacuo
Atrophy of parenchyma
displacement of brain tissue from one compartment to another in response to increased intracranial pressure.
Herniation