L03: The cell surface Flashcards

1
Q

What is a cell membrane made of

A

Phospholipid bilayer with protein molecules scattered through it

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2
Q

What is the phospholipid composed of

A

A phosphate group
A head group
Glycerol
2 fatty acid tails

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3
Q

What is cholesterol made of

A

Polar head
Steroid ring
Hydrocarbon tail

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4
Q

Role of cholesterol

A

To main fluidity and rigidity at 37 degree celcius

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5
Q

What is the function of the membrane

A
  • cell signalling
  • exocytosis
  • same cytoplasm share
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6
Q

What are the types of transport that occur in a cell membrane

A
  • active

- passive

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7
Q

What are the two types of passive transport

A
  • facilitated diffusion

- simple diffusion

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8
Q

What molecules are involved in simple diffusion

A

Simple uncharged molecules

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9
Q

What molecules are involved in facilitated diffusion

A

Large charged molecules

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10
Q

What protein allows facilitated diffusion

A

Ion channels which have a hydrophilic pore

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11
Q

What are the 3 main active transport proteins

A
  • ATP driven pumps
  • light driven pumps
  • coupled proteins
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12
Q

Give an example of ATP- driven pump

A

Sodium potassium ATPase pump

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13
Q

Give two examples of coupled proteins

A
  • uniporter

- symporter

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14
Q

What type of active transport does coupled proteins use

A

2nd active transport and this is using the concentration gradient of one molecule to bring in a different molecule

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15
Q

Example of a uniporter

A

Sodium and calcium in cardiac muscle:
1- 3 sodium bind and go into the cell
2- one calcium go out of the cell

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16
Q

Example of a symporter

A

An example is GLUT-2

  • sodium binds to the symporter and is transported in
  • at the same time glucose binds to the symporter
  • both molecules move the SAME direction
  • this is driven by the sodium electrochemical gradient
17
Q

What is the difference between active and passive transport

A

Passive: molecules go down concentration gradient
Active: molecules go against concentration gradient