krebs cycle Flashcards

1
Q

what feeds into the krebs cycle from the link reaction

A

acetly COA

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2
Q

what then happens to acetly COA

A

coa is released

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3
Q

how is COA released

A

bond broken between acetyl COA and then recyceled back into the link reaction

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4
Q

what is formed after binding of actyle COA and oxelacetate

A

citrate

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5
Q

how is citrate formed

A

from acetly joining oxaloacetate compound

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6
Q

how many carbons are at oxaloacetate

A

4

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7
Q

how many carbons are at citrate

A

6

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8
Q

why are there 6 carbons at citrate

A

becuase the 4 carbon compound of oxaloacetate and the 2 carbon compound of acetyl join to form 6 carbon compound citrate

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9
Q

what forms after citrate

A

5 carbon compound

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10
Q

what forms after the 5 carbon compound

A

4 carbon compound

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11
Q

what does the fad become and why

A

FADH due to reduction

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12
Q

what happens to the fad added

A

it is reduced

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13
Q

when is FAD added

A

after the addition of adp on the 4 carbon compound

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14
Q

describe and explain the krebs cycle (5 marks)

A

-acetyl (2c) binds to oxoelactate (4c) forming citrate (6c)
- COA is released during the binding of acetyl to ozoloactate and is recylced back into krebs cycle
- citrate dcarboxylated
-citrate dehyrdroginated and NAD accepts H+ forming NADH
- 5c compund formed
-5c compound decarboxylated and dehydroginated
- 3x nad is reduced and accepts H+ ions to form 3x NADH
- FAD is oxidised to FADH
- substrate level phosporylation occours in conversion of ADP +Pi to ATP
- oxoloactytate is produced (4c)
- cycle repeates
- 2 turns of krebs cyle form one glucose molecule ( only goes round once for every molecule of pyruvate )

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15
Q

what is the net imput of the krebs cycle

A

3x NAD
ADP + Pi
FAD

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16
Q

what is the net output of the krebs cycle

A

3x NADH
FADH
ATP

17
Q

what converts citrate into 5c compound

A

decarboxylation
dehydrogination
removal of oxygen
hydrogen used to convert nad into NADH

18
Q

what converts 5c compound into 4 carbon compound

A

decarboxylation -removal of co2
dehydrogination - 3x hydrogen molecules are released to convert 3x NAD into 3x NADH
substrate level phosphyrilation (conversion of adp + pi to atp)
conversion of FAD to FADH