KREB CYCLE Flashcards

1
Q

an allosteric enzyme, is inhibited by
NADH, ATP, and succinyl-CoA.

A

Citrate synthase

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2
Q

The _______ provides the energy to drive step 1

A

hydrolysis

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3
Q

Citrate and aconitate are ________; neither has a
stereocenter

A

Achiral

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4
Q

Isocitrate is chiral; it has __ stereocenters and ___
stereoisomers are possible.

A
  • 2
  • 4
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5
Q

is an allosteric enzyme; it is
inhibited by ATP and NADH, and activated by ADP and
NAD+

A

Isocitrate dehydrogenase

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6
Q

This is the first and only energy-yielding step of the
cycle. A molecule of GTP is produced

A

formation of succinate

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7
Q

Malate is ____and can exist as a pair of enantiomers;
It is produced in the cycle as a _____stereoisomer.

A
  • chiral
  • single
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8
Q

what are the three feedback mechanisms of citric acid cycle

A
  • Citrate Synthase
  • Isocitrate dehydrogenase
  • a-Ketoglutarate dehydrogenase complex
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