KPH

Question 1

Which sample would be the preferred type (ie highest sensitivity for the lowest risk) for screening programmes for Down’s syndrome?

Answer 1

A first trimester blood sample

Question 2

If a condition becomes less common in a population, what happens to the positive predictive value for a screening test for that condition?

Answer 2

PPV decreases

Question 3

Which term is used to describe the ability of a screening test to correctly identify people who are at high risk of a particular condition?

Answer 3

Sensitivity

Question 4

How can the problem of over diagnosis in communities be described?

Answer 4

A proportion of cases found to have the disease, detected by the screening programme, would never have experienced symptoms, or progressed during the lifetime but do undergo treatment.

Question 5

Which terms describes how good a test is at identify those who do not have the disease?

Answer 5

Specificity

Question 6

Which organ produces half of the daily production of androgens in all sexes?

Answer 6

The adrenal cortex

Question 7

What is the definition of sensitivity?

Answer 7

How good a test is at identifying people who do have the condition of interest.

Question 8

How do you calculate the false negative rate for a screening test?

Answer 8

Divide the number of people who have the disease but test negative by the total number of people who have the disease.

Question 9

What type of cause is BRCA1 in cancer?

Answer 9

Risk factor