Klebsiella Flashcards

1
Q

List the general characteristics of klebsiella. (gram test, capsule, motility)

A

Gram -ve
capsule present-polysaccharide
non-motile

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2
Q

mostly commonly isolated species?

A

K.pneumoniae

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3
Q

List the main clinical manifestations of K.pneumoniae.

A

sepsis
UTI
bacteremia
meningitis

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4
Q

List the virulence factors for Klebsiella.

A
  • Capsular k antigen
  • Siderophores: taking up iron bound to host proteins
  • Fimbriae: adherence to respiratory and urinary epithelia
  • Endotoxin (LPS)
  • Express outer membrane protein efflux pumps
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5
Q

Pulmonary manifestations of klebsiella?

A

pneumonia lobar
bronchitis
bronchopneumonia

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6
Q

Lab diagnosis of klebsiella?

A

IMViC test= –++

MacConkey- pink and mucoid
CLED- yellow

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7
Q

What antibiotics are used in Klebsiella?

A

Cephalosporins
Fluoroquinolones

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