Klebsiella Flashcards
1
Q
List the general characteristics of klebsiella. (gram test, capsule, motility)
A
Gram -ve
capsule present-polysaccharide
non-motile
2
Q
mostly commonly isolated species?
A
K.pneumoniae
3
Q
List the main clinical manifestations of K.pneumoniae.
A
sepsis
UTI
bacteremia
meningitis
4
Q
List the virulence factors for Klebsiella.
A
- Capsular k antigen
- Siderophores: taking up iron bound to host proteins
- Fimbriae: adherence to respiratory and urinary epithelia
- Endotoxin (LPS)
- Express outer membrane protein efflux pumps
5
Q
Pulmonary manifestations of klebsiella?
A
pneumonia lobar
bronchitis
bronchopneumonia
6
Q
Lab diagnosis of klebsiella?
A
IMViC test= –++
MacConkey- pink and mucoid
CLED- yellow
7
Q
What antibiotics are used in Klebsiella?
A
Cephalosporins
Fluoroquinolones