Klebsiella Flashcards

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1
Q

General characteristics (3)

A

NON-MOTILE

POLYSACCHARIDE CAPSULE

LACTOSE-FERMENTING, PINK, MUCOID (due to capsule) colonies on MACKONEY agar

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2
Q

Klebsiella species (6)

A
K.pneumoniae 
K.aerogenes
K.rhinoscelromatis
K.ozaenae
K.oxytoca
K.granulomatis
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3
Q

Nosocomial infections (3)

A

UTI

Respiratory tract infection (bronchopneumonia)

Wound infection

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4
Q

Rhinoscelroma

A

(By K.rhinoscelromatis)

Granulomatous infiltration of submucosa affecting nose, larynx, throat, trachea

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5
Q

Ozaena

A

(By K.ozaenae)

Atrophic rhinitis (wasting of nasal mucosa)

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6
Q

Antibiotic-associated Hemorhhagic Colitis

A

(By K.oxytoca)

Main cause —> Clostridium difficile

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7
Q

Donovanosis

A

(By K.granulomatis)

STD

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8
Q

Virulence Factors (6)

A

1- LONG CHAIN LPS —> Protects from OPSONIZATION and COMPLEMENT
2- CAPSULE —> Protects from PHAGOCYTOSIS
3- FIMBRIAE (Type 1) —> ADHESION to tissues
4- SIDEROPHORE —> IRON AQCUSITION
5- HYPERMUCOVISOSITY —> (excessive polysaccharide capsule production) —> confers HIGH SERUM RESISTANCE and correlates HIGHLY INVASIVE infection (LIVER ABSCESS)
6- ESBL and CARBAPENEMASE —> VIRULENCE and OUTBREAKS

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9
Q

How are capsular types determined?

A

Quellung reaction (agglutination)

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