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Ma-301 therapeutische oncologie > klassieke medicatie niet-cyclus specifiek > Flashcards

klassieke medicatie niet-cyclus specifiek Flashcards

1
Q

Chloorambucil

A

Alkyleerders, stikstofmosterderivaten

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2
Q

Melfalan

A

Alkyleerders, stikstofmosterderivaten

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3
Q

Carmustine

A

Alkyleerders, stikstofmosterderivaten

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4
Q

Bendamustine

A

Alkyleerders, stikstofmosterderivaten

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5
Q

Busulfan

A

Alkyleerders, alkylsulfonzuurderivaten

TDM vanwege tox:

  • Veno-oclussieve ziekte van de lever
  • Graft versus host disease
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6
Q

Treosulfan

A

Alkyleerders, alkylsulfonzuurderivaten

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7
Q

Cyclofosfamide

A

Alkyleerders, Oxazofosforinen

profylaxe hemorragische cystitis: hyperhydratie en MESNA

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8
Q

Ifosfamide

A

Alkyleerders, Oxazofosforinen

profylaxe hemorragische cystitis: hyperhydratie en MESNA

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9
Q

Dacarbazine

A

Alkyleerders, overig

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10
Q

Lomustine, passeert BHB

A

Alkyleerders, overig

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11
Q

Procarbazine

A

Alkyleerders, overig

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12
Q

Temozolomide

A

Alkyleerders, overig

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13
Q

Thiotepa

A

Alkyleerders, overig

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14
Q

Cisplatin

A

Platina-verbindingen
Hoog-emetogeen
Ontsteking MD-kanaal

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15
Q

Carboplatin

A

Platina-verbindingen
Calvert-formule: Dosering in (mg)= AUC x (GFR+25)
AUC correleert beter met toxiciteit en effectiviteit

  • trombocytopenie
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16
Q

Oxaliplatin

A

Platina-verbindingen
Dichtgeknepen keel
Oplossen in 5% glucose, GEEN NaCl

17
Q

Doxorubicine

A

Antracyclinederivaten

  • cumulatieve dosis 450-550
18
Q

Epirubicine

A

Antracyclinederivaten

  • cumulatieve dosis 900
19
Q

Daunorubicine

A

Antracyclinederivaten

20
Q

Mitoxantron

A

Antracyclinederivaten

21
Q

Bleomycine

A

Cytotoxische antibiotica

longschade (cumulatieve dosis)

Ma-301 therapeutische oncologie (7 decks)

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