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Kinetics Flashcards

1
Q

CYP 1A2 Induction

A

CROMN

carbamazepine
rifampin
omeprazole
modafinil
nafcillin

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2
Q

CYP 1A2 Inhibitors

A

FED MACCEN

fluvoxamine
efavirenz
diltiazem
mexiletine
amiodarone
cimetidine
ciprofloxacin
erythromycin
norfloxacin

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3
Q

CYP 2C9 Inducers

A

PPERR

phenobarbital
phenytoin
enzalutamide
rifampin
rifapentine

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4
Q

CYP2C9 Inhibitors

A

FFB PAVES FILM

fenofibrate
fluconazole
Bactrim
paroxetine
amiodarone
voriconazole
efavirenz
sertraline
fluvoxamine
isoniazid
lovastatin
metronidazole

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5
Q

CYP 2C19 Inhibitors

A

CFFPT LIKE MOOV

celecoxib
fluoxetine
fluvoxamine
pantropazole
topiramate
lansoprazole
isoniazid
ketoconazole
esomeprazole
modafinil
omeprazole
oxcarbazepine
voriconazole

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6
Q

CYP 3A4 inducers

A

MEEN COPPPRS

modafinil
efavirenz
enzalutamide
nevirapine
carbamazepine
oxcarbamazepine
phenobarb
phenytoin
pioglitazone
rif-drugs (rifampin, etc)
St Johns Wort

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7
Q

CYP 3A4 Inhibitors

A

several anti-virals
conazoles (flucon, itra, keto, vori)

SAVE DICCA

amiodarone
aprepitant
cimetidine
clarithromycin
diltiazem
erythromycin
imatinib
suboxone
verapamil

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8
Q

Main substrates CYP
1A2

A

tylenol
amitriptyline
caffeine
clozapine
clozapine
estradiol
fluvoxamine
haloperidol
imipramine
mirtazapine
olanzapine
ropinirole
warfarin - R enantimer
theophylline
zolmatriptan

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9
Q

Main substrates CYP
2C9

A

amitriptyline
celecoxib
diclofenac
fluoxetine
sulfonylureas
ibuprofen
indomethacin
irbesartan
losartan
phenytoin
rosuvastatin
warfarin - S
tamoxifen

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10
Q

Main substrates CYP
2C19

A

amitriptyline
cilostazol
citalopram
clopidogrel
diazepam
imipramine
lansoprazole
naproxen
omeprazole
pantoprazole
phenobarbital
phenytoin
propranolol

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11
Q

Main substrates CYP
2D6

A

amitriptyline
aripiprazole
atomoxetine
carvedilol
clozapine
codeine
dextromethorphan
donepezil
duloxetine
flecainide
fluoxetine
fluvoxamine
haloperidol
hydrocodone
imipramine
metoprolol
mirtazapine
nebivolol
nortriptyline
oxycodone
paroxetine
propafenone
propranolol
risperidone
tamoxifen
timolol
tramadol
trazodone
venlafaxine

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12
Q

CYP 2C19 Inducers

A

CREEPPS

carbamazepine
rifampin
efavirenz
enzalutamide
phenobarb
prednisone
St Johns Wort

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13
Q

CYP 2D6 Inhibitors

A

amiodarone
bupropion
celecoxib
cimetidine
cinacalcet
benadryl
duloxetine
escitalopram
fluoxetine
haloperidol
methadone
metoclopramide
midodrine
paroxetine
propafenone
quinidine
ritonavir
sertraline
terbinafine

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14
Q

CYP 3A4

A

amiodarone
amlodipine
aprepitant
aripiprazole
atorvastatin
buspirone
carbamazepine
cilostazol
citalopram
clarithromycin
cyclosporine
dapsone
benzos
diltiazem
donepezil
eplerenone
erythromycin
estradiol
fentanyl
finasteride
irinotecan
conazoles
lidocaine
lovastatin
mirtazapine
nifedipine
quetiapine
quinidine
sertraline
sildenafil
-limus drugs
TCA’s
trazodone
verapamil
ziprasidone
ambien
zonisamide

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Notes (12 decks)

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