KIN 401 Test 1 Flashcards
GH: Hormone Type
Peptide
GH: Mechanism of Release
Hormonal
GH: Endocrine Organ (released by)
Anterior Pituitary
GH: Target Tissues
Adipose tissue
Muscle
Liver
GH: Target actions
IGF synthesis
Promotes cell division and cell proliferation
Facilitates protein synthesis
Slows carb breakdown
ADH: Hormone Type
Peptide
ADH: Mechanism of release
Humoral/Neural
ADH: Endocrine organ (released by)
Posterior pituitary
ADH: Target tissues
Kidneys
ADH: Target actions
Promotes water absorption in kidneys
Preserves plasma volume & body fluids
Oxytocin: Hormone type
Peptide
Oxytocin: Mechanism of release
Neural
Oxytocin: Endocrine organ (released by)
Posterior pituitary
Oxytocin: Target tissues
Breast tissue
Uterus
Oxytocin: Target actions
Initiates muscle contraction in uterus
Stimulates milk production during lactation
Thyroxine (T4): Hormone type
Amine
Thyroxine (T4): Mechanism of release
Hormonal
Thyroxine (T4): Endocrine organ (Released by)
Thyroid
Thyroxine (T4): Target tissues
Everyone except brain, spleen, uterus, testes, thyroid
Thyroxine (T4): Target actions
Raises metabolic rate
Regulates tissue growth & development, skeletal & nervous system formation, maturation, and reproduction
Triiodothyronine (T3): Hormone type
Amine
Triiodothyronine (T3): Mechanism of release
Hormonal
Triiodothyronine (T3): Endocrine organ (released by)
Thyroid
Triiodothyronine (T3): Target tissues
Many tissues
Triiodothyronine (T3): Target actions
Facilitates neural reflex activity
Helps maintain blood pressure by increasing adrenergic receptors in blood vessels
Calcitonin: Hormone type
Peptide
Calcitonin: Mechanism of release
Humoral
Calcitonin: Endocrine organ (released by)
Thyroid
Calcitonin: Target tissues
Bones
Calcitonin: Target actions
Promotes calcium into bone: inhibits osteoclasts and stimulates osteoblasts
Regulates high calcium levels
Parathyroid hormone: Hormone type
Peptide
Parathyroid hormone: Mechanism of release
Humoral
Parathyroid hormone: Endocrine organ (released by)
Parathyroid gland
Parathyroid hormone: Target tissues
Small intestine
Bone
Kidneys
Parathyroid hormone: Target actions
Responds to low calcium levels
Activates osteoclasts, releases calcium and phosphate into bone
Enhanced calcium reabsorption
Increased calcium absorption into small intestine
ACTH: Hormone type
Peptide
ACTH: Mechanism of release
Hormonal
ACTH: Endocrine organ (released by)
Anterior pituitary organ
ACTH: Target tissues
Adrenal cortex
ACTH: Target actions
Cortisol & aldosterone release
Promotes FFA mobilization from adipose cells
Norepinephrine: Hormone type
Amino-acid
Norepinephrine: Mechanism of release
Neural
Norepinephrine: Endocrine organ (released by)
Adrenal medulla & SNS
Norepinephrine: Target tissues
Many tissues, heart, blood vessels, liver, adipose tissue
Norepinephrine: Target actions
Systemic vasoconstriction
Increased myocardial contractility
Accelerated SA node depolarization
Epinephrine: Hormone type
Amino acid
Epinephrine: Mechanism of release
Neural
Epinephrine: Endocrine organ (released by)
Adrenal medulla
Aldosterone: Endocrine organ (released by)
Adrenal cortex
Epinephrine: Target tissues
Many tissues, heart, blood vessels, liver, adipose tissue
Epinephrine: Target actions
Increased myocardial contractility
Accelerate SA node depolarization
Increased glycogenolysis
Aldosterone: Hormone type
Steroid
Aldosterone: Mechanism of release
Humoral/Hormonal
Aldosterone: Target tissues
Kidney
Aldosterone: Target actions
Controls total sodium concentration and extracellular fluid volume
Stimulates sodium reabsorption in distal kidney tubules
Cortisol: Hormone type
Steroid
Cortisol: Mechanism of release
Hormonal
Cortisol: Endocrine organ (released by)
Adrenal cortex
Cortisol: Target tissues
Many tissues, liver, adipose, muscle
Cortisol: Target actions
Increased breakdown of protein to amino acids for gluconeogenesis in the liver
Insulin antagonist- inhibits cellular uptake and oxidation
Increased triglycerol breakdown in adipose tissue
Testosterone: Hormone Type
Steroid
Testosterone: Mechanism of release
Hormonal
Testosterone: Endocrine organ (released by)
Ovaries
Testes
Testosterone: Target tissues
Organs
Muscles
Bones
Skin
Hair
Testosterone: Target actions
Initiates sperm production
Stimulates development of male secondary sex characteristics
Estradiol: Hormone type
Steroid
Estradiol: Mechanism of release
Hormonal
Estradiol: Endocrine organ (released by)
Ovaries
Estradiol: Target tissues
Blood vessels
Bone
Prostate
Lungs
Liver
Testes
Intestine
Estradiol: Target actions
Regulates ovulation, menstruation, and physiologic adjustments during pregnancy
Increases FFA mobilization from adipose tissue and glucose reuptake
Progesterone: Hormone type
Steroid
Progesterone: Mechanism of release
Hormonal
Progesterone: Endocrine organ (released by)
Ovaries
Adrenal glands
Progesterone: Target tissues
Uterus
Progesterone: Target actions
Contributes regulatory input to female reproductive cycle, uterine smooth muscle action, lactation
Insulin: Hormone type
Peptide
Insulin: Mechanism of release
Humoral
Insulin: Endocrine organ (released by)
Pancreas (B cells)
Insulin: Target tissues
All tissues but brain
Insulin: Target actions
Promotes lipid, protein, and glycogen synthesis
Regulates all glucose entry via GLUT-4 translocation
Glucagon: Hormone type
Peptide
Glucagon: Mechanism of release
Humoral
Glucagon: Endocrine organ (released by)
Pancreas (a cells)
Glucagon: Target tissues
Adipose
Liver
Glucagon: Target actions
Regulates blood glucose levels during PA as glycogen store are depleted
Leptin: Hormone type
Peptide
Leptin: Mechanism of release
Hormonal
Lepin: Endocrine organ (released by)
Adipose tissue
Leptin: Target tissues
Brain (hypothalamus)
Laptin: Target actions
Signals satiety
Ghrelin: Hormone type
Peptide
Ghrelin: Mechanism of release
Humoral
Ghrelin: Endocrine organ (released by)
Stomach
Ghreline: Target tissues
Brain (hypothalamus, amygdala)
Ghrelin: Target actions
Signals hunger