Kin 311 Mid Term 2 Flashcards
Diabetes and metabolic disorders
t1 d - Born with it - result of pancreatic beta cell destruction causing
t2 d - develops due to lifestyle genetics etc and insulin resistence insulin is less effective at facilliating glucose uptake
gestational diabetes - glucose inteolerance onset during pregnancy
glucose measurement
Important for the diagnosis of diabetes
important for the monitoring of glucose at rest during and following exercise
Capillary glucose sampling
Normal blood glucose
Fasted anything below 5.5mmol/l ot 100mg/dl is normal and unfasted anything below 11.1mmol/L or 200mg/dl is normal
Capillary sampling according to WHO
Select clean site with aalc punch skin with deliberate poke prevent repeated punctures
wupe away first drop of blood aviod contamination with tssue fluid or debris
avoid squeezing teh finger too tightly because tgis dilutes the sample with tissue fluid or plasma
Glucose tolerance test
Essentially just drink a fuck ton of glucose in a very short period of time like 5 min then track what occurs post 1-5 hours will see a spije in the following hrs then go back to nors
continuous glucose minotring if we take values at intervals we erisk vauable information being left out continous monitoring is better as we capture and can visualize the highs and lows
Glycated hemoglobin
Glucose damaged hemoglobin as RBC are freely permeable to glucose molecules and have a life span of 2-3 months fo you can take glucose levels over the preceduing 2-3 months
Advantages and disadvantages of diagnostic tests for diabetes
Finger prick adv- Standard easy single sample dis - not stable high variability
2 hour post glucose Adv - standard predicts microvascular complications sample not stanle high variability involnvenient 13 12.15
WHy do we measure PA levels
Direct relatipnship with disease endpoints
indirect relationship with disease through the effects of activity on diet or body weight
ability to study PA patterns determinants and barrier in differnt groups
more relevant for a wider segment of pop
evaluate PA interventions
Measuring energy expensiture
PA - bodily movement generated by skeletal muscles resulting in energy expenditure ie heat production
What are the 2 enegry expenditure divisions
Non exercice activity thermogenesis (NEAT) which are things we dont rly think about but over time could make a difference ie fidgeting blinking etc and the second one is voluntary physical activity
Metabolic cart
Measure oxygen used and taken up
Metabolic chamber
you live in it and it measures heat energy what is produced can measure over logn periods of time
Doubly labelled water technique
Essentially just means having more isotopes of molecules when yo uburn it you metabolise CO@ and hydorgen ions the ratio of oxygen to hydrogen can tell you how metabolically active you are over months
Classifying energy expendtiture (MET)
1 met oxy consumed at rest
normalized metabolic demand of a given activity across activities the data for the value of 1 met is 3.5 ml o2 min times kg body weight was done by 1 person
Physcial inactivity
An insuffiencent PA level to meet present PA recommendations
Sitting
a position in which ones weight is supported by cuttock rather than feet and back is upright you can be sitting sedentarily or you can be doing something else like biking
lying
being in a horozontal position on a supporting surface
standing
A position in which one has or is miantaining an upright position while supported by ones feet
the common theme with all of these is about what you are doing in the said positions
Sedentary behavior
any WAKING behavior charectirsed by a EE of less tha 1.5 mets while in a sitting reclining or lying position STANDING NOT INCLUDED
Moveent behaviors not mutally exclusive
you cna be active and sedentary at the same time the best way to mitigate thigs is by minimiznng sedentary behaviors
Weekend warriors
Essentially just says it doesnt matter how you get the minutes in as ling as you are getting all the required minutes in
Nethods for assessing PA in activity (PA questionairs pros cons and what are some good ones (International PA 1
Pros - self reported mass use cheap
cons - social desireability will be biased to themselves, wont remember everything, familiarity iwth terms
Good ones are the IPAq and the GPAQ
IPAQ - developed over 20 years many valitative studies validity ranges from good to poor depending on outcome activity type and cohort
Subjective assessment method - Pedometer how does it work pros cons what is better
- self report measures of PA
Step counters - detect vertical accelerations of body record count when vertical acceleration excees threshpld value, so not very good with super slow speeds but accurate for number fo steps taken and distance walked step count better than kilocalorie estimates
Limitations - less sensitive if tileted away from vertical plane so must be worn properly and also for obese may fail to record steps at slow pace
whats better is an ankle device which is sensitive enough to detect frail slow shufflunng steps so better accuracy
Acceloerometer how does it wirk pros cons give example of one
measure movement based on accleration deceleration any type of moveemtn worn on trunk or limbs provides FIT of PA measures in all 3 planes not very good ith cycling or swimming
good one fore that is the active pal
pros - small data over long periods download data can be worn by different people easy to track
cons - more reasources and time than pedometer, need technical expertise single plane models not accurat for bike swimming
cant deetch incresed activity level from upper body movement carrying laod or surface changes like hills
equasions that estimate EE may not apply to free living situations
Heart rate monitors
linearly related to vo2 during submax aerobic activities
good method of PA assessment
very practical in the field
able to store data estimation of FIT of PA for days to weeks
indirect calorimetry is highly correlated with HR monitoring stronger correlation accelerometers vs valoriometry for lifestyle activities
wearing an accelerometer and. HR monitor toegtehr may imrpove EE estimation and classification of time spent in light moderate and hard atcivity
limitations - HR incresed by temp humidity high altitude can result in overest of EE
also influenced by emotional state hydration status type of contraction and amount of muscle mass recruited will afect Hr independent of PA level
Other devices
Monitors that use muliple inputs some monitos use a combo of acclerometer and physiological signals to preduct and calculate energy expentidture like the sensewear armband and the actiheart
GPS can provoide accuract assessment of speed ranging from slow walking to rast running and can be sued indoor or outside cant be used for stationary activities like biking physiological sensors embedded into clothing with wearable digital cameral may be useful in future
General PA guidelines
0-4 years ofl 180 mins per day of activity and when reach 5 YOA 60 mins of energetic play no screen time for 0-2 2-4 1 hr of screen time
for us 150 mins per week in 10 mins or more bouts
older adults more focus on bone strentthan and muscle building of major muscle groups
What can vo2 predict
extreame predictor of all cause morbidity and mortality