Kidneys + Excretion Flashcards
Proximal convoluted tubule
Close to Bowman’s capsule
- Ion + water reabsorption
- Na+ actively reabsorbing Cl- passively follows
- Water passively reabsorbed (goes where party is)
- Urine composition does not change
Convoluted =
Complex / twisted
Distal convoluted tubule
Farther away from Bowman’s capsule
- Alters urine composition
- Active NaCl reabsorption (some water follows)
- Extra “free” water that needs to be excreted = U/P <1
- Altered by anti-diuretic hormone = alters water permeability
Low ADH in distal convoluted tubule =
Diuresis = dilute urine (U/P<1)
- Poorly permeable to water
High ADH in distal convoluted tubule =
Anti-diuresis = concentrated urine (U/P >1)
- Highly permeable to water
Describe the mammals convoluted tubules?
Cortex (Proximal convoluted tubule) –> deep in the medulla (Loop of Henle) –> Cortex (Distal convoluted tubule) –> deep in medulla (Collecting duct)
Purpose of Loop of Henle?
Sets up NaCl concentration in interstitial fluid
Describe the process of the Loop of Henle?
- Descending + ascending limb –> urine flowing in opposite directions
- Ascending limb = NaCl actively transported out, water cannot follow
- Descending limb = permeable to water, water moves out due to NaCl actively transported out the ascending limb
Anti-diuresis
Concentrated urine
- Dilute urine coming in distal convoluted tubule –> water moves out –> urine starts to concentrate
- Urine lows down collecting duct it encounters higher and higher NaCl in interstitial fluid –> water moves out –> concentrate urine
- High ADH
Diuresis =
Dilute urine
- DCT + collecting duct become poorly permeable to water
- Water remains in nephron = dilute urine
Nitrogen excretion - Ammonia
Marine invertebrates, freshwater & marine fishes, tadpoles
- Highly toxic
-Highly soluble
- Cheap - no ATP
Nitrogen excretion - Urea
Amphibians, turtles, mammals
- Less toxic
- Highly soluble but requires less water to excrete
- More costly (4-5 ATP)
Nitrogen excretion -Uric Acid
Birds, lizards, snakes, terrestrial invertebrates, spiders, scorpions
- Lowest toxicity
- Lowest solubility requires lowest water to excrete
- Most costly