Kidneys Flashcards
Renal corpuscle
Top = parietal epithelium, bowman’s space, podocyte (visceral epi) and capillary
Middle = mesangial cells in mesanglial matrix
Bottom = endothelial cells
top = parietal epithelium then bowman’s space
next cells - podocytes (visceral epithelium) and capillary
mesangial cell in mesangial matrix
top line = endothelial cell
bottom line = capillary
podocytes on surface of glomellular capillaries
glomerulus with interconnected capillaries on top
podocyte cell body showing primary and secondary foot processes
Podocytes
white is bowman’s space
Glomeullar capillaries
1= bowman’s space
2 = fenestrated cap
filtration barrier
comprised of
mesangial cells and mesangial matrix
mesangial cells and mesangial matrix plastic embedded
1 = proximal convoluted
2 = distal convoluted
more red = PCT
less red = DCT
think about why it is staining red with acid phosphatase!! lysosomes!!!
endocytic vessicles
proximal convoluted tubule
THINK: microvilli, endocytic vessicles, lysosomes, mitochondria, lateral PM interdigitation, basal PM infoldings
infoldings of basal plasma membranes containing mitochondia = typical of ion transport membranes
*contain NA KTPase pump
typical ion transporting scheme
lateral PM interdigitation with indistinct cell borders
Basal PM infldings contain mitochondria with sodium pumps
distal convoluted tubule
NOTE: no brush border, sparse microvilli, nucleus at upper portion of cell, basal plasma membrane infoldings, mitochondria
limbs of loop of henle and vasa recta
loop of henle
NOTE: simple squamous epithelial cells, no brush borders, few organelles, no basolateral interdigitation
*arrow = nearby vasa recta
collecting ducts
NOTE: pale staining cells that go cuboidal to columnar, lack brush border and have distinct cell border
macula densa
L arrow = macula densa
R arrow = extra golmerular mesangial cells
arrows pointing to JG cells containing granules
*secreted into circulation in response to decreased sodium concentration in tubular fluid (promoted by signaling from macula densa)
outer wall of bladder has three layers of smooth muscle
