Kidneys Flashcards

1
Q

Plasma K+ concentration

A

4mEq/L

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2
Q

Urine [K+]

A

20-70 mEq/L

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3
Q

Plasma [Urea]

A

10 mEq/L

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4
Q

Urine [Urea]

A

300 mEq/L

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5
Q

Plasma [Creatinine]

A

0.001 mEq/L

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6
Q

Urine [Creatinine]

A

10 mEq/L

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7
Q

Is glucose expelled in urine?

A

No

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8
Q
Parts of the nephron, in order
1
2
3
4
5
6
7
A

1) Bowman’s capsule
2) Proximal tubule
3) Descending limb
4) Loop of Henle
5) Ascending limb
6) Distal tubule
7) Collecting duct

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9
Q

What occurs between the glomerulus and Bowman’s capsule?

A

Filtration

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10
Q

Which blood vessels run beside the tubules?

A

Peritubular capillaries

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11
Q

Where does reabsorption occur?

A

Between tubule and peitubular capillaries

Proximal tubule
Descending, ascending limbs
Distal tubule
Collecting duct

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12
Q

Where does secretion occur?

A

From peritubular capillaries to tubule

Proximal tubule
Distal tubule
Collecting duct

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13
Q

What determines the amount of solute excreted?

A

Amount filtered - amount reabsorbed + amount secreted

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14
Q

What structure gives rise to peritubular capillaries?

A

Efferent arteriole

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15
Q

What do the peritubular capillaries become?

A

Renal vein

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16
Q

What is secreted?

A

K+

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17
Q
What is filtered?
1
2
3
4
5
6
7
8
A

1) Na
2) Water
3) K
4) Ca
5) PO4
6) Glucose
7) Creatinine
8) Urea

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18
Q

Where does water reabsorption occur?

A

Descending limb

Collecting duct

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19
Q

Where does Na reabsorption occur?

A

Ascending limb

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20
Q
What is reabsorbed?
1
2
3
4
5
6
7
A

1) Water
2) Na
3) K
4) ca
5) PO4
6) Glucose
7) Urea

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21
Q

Water excretion

22
Q

Na excretion

23
Q

K excretion

24
Q

Ca excretion

25
PO4 excretion
20%
26
Glucose excretion
0%
27
Creatinine excretion
100%
28
Urea excretion
50%
29
What is filtration?
Movement of plasma and solutes from the glomerulus into Bowman's capsule
30
What is reabsorption?
Movement of water and solutes from the lumen into the peritubular capillaries Can be active or passive
31
What is secretion?
Active transport of solutes from the peritubular capillaries into the renal lumen
32
What is Bowman's capsule made up of?
Capsular epithelium
33
What is wrapped around glomerular capillaries?
Podocytes
34
What do podocytes wrap around?
Glomerular capillaries
35
Which structure is in contact with the afferent and efferent arterioles?
Ascending limb of loop of Henle
36
Function of podocytes
Foot processes surround each capillary Leave gaps where filtration can take place
37
What binds together glomerular capillaries?
Mesangial cells
38
What do solutes move through in filtration? 1 2
1) Endothelial pores | 2) Between podocyte foot processes
39
Volume of plasma filtered through glomerulus and Bowman's capsule
20%
40
Amount of plasma reabsorbed from nephron
<19% (20% of plasma was filtered)
41
Amount of filtered plasma excreted
1%
42
Ph
Hydrostatic pressure
43
Pi
Colloid osmotic pressure
44
Pfluid
Pressure created by fluid in Bowman's capsule
45
Net filtration pressure
Hydrostatic pressure - colloid osmotic pressure - Fluid pressure in Bowman's capsule Ph - Pi - Pfluid
46
Does hydrostatic pressure promote or inhibit filtration?
Promote
47
Pressure of hydrostatic pressure
+55mmHg (into Bowman's capsule)
48
Does colloid osmotic pressure promote or inhibit filtration?
INhibit
49
Pressure of colloid osmotic pressure
-30mmHg (out of Bowman's capsule)
50
Does Pfluid promote or inhibit filtration?
Inhibit
51
Pressure of Pfluid
-15mmHg (out of Bowman's capsule)
52
Net filtration pressure
10mmHg