Kidney Ultra-filtration Flashcards

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1
Q

Glomerulus structure of basement membrane

A

First layer - endothelium of blood capillary with pores to allow blood plasma to seep out

Second layer : pedocytes which form lining of bowmans capsule

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2
Q

Pedocytes cells

A

Projecting fingers that wrap around cappilaries of glomerulus

Tiny slits left between interlocking pedo cells to allow substances to move through

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3
Q

Ultra filtration

A
  • occurs in renal capsule (bowmans) in nephron
  • small molecules filtered out of the blood and pads into lumen of neohonr
  • blood in glomerular is separated by the two layers of cells
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4
Q

How does ultrafiltration happen

A
  • blood flows into glomerulus through affefent arteriole which has WIDER diameter than efferent
  • diff in diameter ensures blood in cappilaries on glom maintains higher pressure than pressure in bowmans capsule
  • press difference pushed fluid out of glom and into bowmans through pores in pedocytes
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5
Q

What is filtered out of blood

A
  • water
  • amino acid
  • glucose
  • urea
  • inorganic mineral ions
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6
Q

What’s left in the cappilaries

A

•blood cells and proteins because they have lower water potential than blood

Low water potential ensures :
•some water stays within the blood
•ensures water is reabsorbed at a later stage

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