KIDNEY TRANSPLANT Flashcards

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1
Q

What is the treatment of choice for most patients with end-stage kidney disease (ESKD)?

A

Kidney transplantation

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2
Q

Is kidney transplantation an emergency procedure?

A

No, it is an elective procedure

Patients should be in the best possible condition prior to transplantation.

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3
Q

What types of donors can provide kidneys for transplantation?

A

Living or deceased donors

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4
Q

What is paired donor exchange in kidney transplantation?

A

Recipients swap willing donors

This contemporary development increases transplant opportunities.

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5
Q

What are some contraindications for kidney transplantation?

A

RASCCIH

Recent malignancy

Active or chronic infection

Severe irreversible extrarenal disease

Class II obesity (BMI>35 kg/m2)

Current substance abuse

Inability to give informed consent

History of nonadherence to treatment regimen

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6
Q

Where is the transplanted kidney typically placed in the recipient’s body?

A

In the iliac fossa anterior to the iliac crest

This location allows for easier access to the blood supply.

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7
Q

What is an important indicator of the overall success of kidney transplantation?

A

The production of urine after blood supply restoration

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8
Q

What are the goals of preoperative management for kidney transplantation?

A

NEP

Normalize metabolic state

Ensure patient is infection-free

Prepare patient for surgery

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9
Q

What tests are performed to assess compatibility before kidney transplantation?

A

TBA

Tissue typing

Blood typing

Antibody screening

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10
Q

What medications are prescribed after kidney transplantation?

A

Immunosuppressive medications

They prevent transplant rejection but leave the patient at risk for infection.

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11
Q

An immediate antibody-mediated reaction that occurs within 24 hors after transplant. It leads to generalized glomerular capillary thrombosis and necrosis and requires the immediate removal of the transplanted organ.

A

Hyperacute rejection

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12
Q

How soon can acute rejection occur after kidney transplantation?

A

Within 3 to 14 days

Symptoms include tenderness at the transplant site and a decrease in serum creatinine.

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13
Q

What are common signs of transplant rejection that nurses should assess for?

A
  • Oliguria
  • Edema
  • Fever
  • Increasing blood pressure
  • Weight gain
  • Tenderness over the transplanted kidney

Early detection of these signs is crucial for effective management.

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14
Q

What complications can arise from immunosuppressive therapy after kidney transplantation?

A
  • Nephrotoxicity
  • Hypertension
  • Hyperlipidemia
  • Hirsutism
  • Tremors
  • Blood dyscrasias
  • Cataracts
  • Gingival hyperplasia
  • Several types of cancer
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15
Q

What postoperative care is essential for the organ donor?

A
  • Pain management
  • Fluid and electrolyte monitoring
  • Follow-up care

Donors require similar care to recipients after the procedure.

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16
Q

True or False: A kidney from a cadaver donor usually begins to function immediately after surgery.

A

False

Cadaver donor kidneys may take 2 to 3 weeks to function.

17
Q

A cadaver donor may undergo _____ before it could function

A

ATN
Acute tubular necrosis

18
Q

To optimize the physical status of patient receiving kidney transplant, the patient should be on

A

Dialysis a day before procedure

19
Q

To optimize the physical status of patient receiving kidney transplant, the patient should be on

A

Dialysis a day before procedure

20
Q

Patient receiving cyclosporin may not exhibit symptomatic signs and symptoms of acute rejection, therefore, the asymptomatic sign would be?

A

Rise in serum creatinine level by 20%

21
Q

Signs and symptoms of infection post operatively

A

SFRI

Shaking chills

Fever

Rapid heart and respiration rate

Increase or decrease in WBC